ArticleChemical communications (Cambridge, England)2011
In vivo cell death mediated by synthetic ion channels.
Article in Chemical communications (Cambridge, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 27 citations in OpenAlex.
- Supramolecular macrocyclic artificial ion channels for biomedical applications.Fundamental research · 2025Review
- Recent Advances in Bioactive Artificial Ionophores.Chembiochem : a European journal of chemical biology · 2021Review
- Polyhydrazide-Based Organic Nanotubes as Efficient and Selective Artificial Iodide Channels.Angewandte Chemie (International ed. in English) · 2020Article
- A halogen bond-mediated highly active artificial chloride channel with high anticancer activity.Chemical science · 2018Article
- Hydraphiles: a rigorously studied class of synthetic channel compounds with in vivo activity.International journal of biomedical imaging · 2013Article
- Biomarkers and molecular probes for cell death imaging and targeted therapeutics.Bioconjugate chemistry · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Synthetic ion channel hydraphiles, which are known to infiltrate membranes and disrupt ion homeostasis, were tested as direct injection toxins in live mice as potential schlerotic agents. The study uses a near-IR dye to image and evaluate the success of the approach.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.