ArticleJournal of virology2011
Phylogeography and evolutionary history of reassortant H9N2 viruses with potential human health implications.
Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 166 citations in OpenAlex.
- Phase I/II randomized double-blind study of the safety and immunogenicity of a nonadjuvanted vero cell culture-derived whole-virus H9N2 influenza vaccine in healthy adults.Clinical and vaccine immunology : CVI · 2015Trial
- Article
- Pathogen identification and analysis of broiler bronchial obstruction syndrome using high-throughput sequencing technology.Poultry science · 2026Article
- Genetic and biological characterization of H9N2 avian influenza viruses isolated from swine in China.BMC veterinary research · 2026Article
- Two decades (2005 to 2025) of avian influenza research trends, knowledge gaps and distribution of emerging H5N1 2.3.4.4b clade in South Asia.One health outlook · 2026Article
- Genetic diversity of H9N2 avian influenza viruses in Iran over the past two decades.Veterinary research forum : an international quarterly journal · 2026Article
- Isolation, characterization and phylogenetic analyses of avian influenza A (H9N2) viruses isolated from poultry between 2019 and 2023 in Egypt.BMC veterinary research · 2025Article
- Identification & genetic & virological characterisation of a human case of avian influenza A (H9N2) virus from Eastern India.The Indian journal of medical research · 2025Article
- PB2 627V and HA 217 sites synergistically affect the lethality of H9N2 in mice.Virologica Sinica · 2025Article
- A comprehensive pathological and molecular investigation of viral co-infections in ducks in Egypt.Frontiers in microbiology · 2025Article
- Pathology and molecular detection of influenza A subtype H9N2 virus in commercial poultry in Nigeria, 2024.Open veterinary journal · 2024Article
- Proposal for a Global Classification and Nomenclature System for A/H9 Influenza Viruses.Emerging infectious diseases · 2024Article
- Rapid adaptive substitution of L226Q in HA protein increases the pathogenicity of H9N2 viruses in mice.Infectious medicine · 2024Article
- Genetic insights of H9N2 avian influenza viruses circulating in Mali and phylogeographic patterns in Northern and Western Africa.Virus evolution · 2024Article
- Vaccination and Antiviral Treatment against Avian Influenza H5Nx Viruses: A Harbinger of Virus Control or Evolution.Vaccines · 2023Review
- Antibody prevalence to avian influenza virus subtypes H5, H7 and H9 in falcons, captive and wild birds, United Arab Emirates, 2003-2006.Veterinary medicine and science · 2023Article
- Has avian influenza virus H9 originated from a bat source?Frontiers in veterinary science · 2023Article
- Article
- Selection of an Optimal Recombinant Egyptian H9N2 Avian Influenza Vaccine Strain for Poultry with High Antigenicity and Safety.Vaccines · 2022Article
- Emerging threats and vaccination strategies of H9N2 viruses in poultry in Indonesia: A review.F1000Research · 2022Review
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 10 institutions in 7 countries.
Funding
Abstract
Avian influenza viruses of the H9N2 subtype have seriously affected the poultry industry of the Far and Middle East since the mid-1990s and are considered one of the most likely candidates to cause a new influenza pandemic in humans. To understand the genesis and epidemiology of these viruses, we investigated the spatial and evolutionary dynamics of complete genome sequences of H9N2 viruses circulating in nine Middle Eastern and Central Asian countries from 1998 to 2010. We identified four distinct and cocirculating groups (A, B, C, and D), each of which has undergone widespread inter- and intrasubtype reassortments, leading to the generation of viruses with unknown biological properties. Our analysis also suggested that eastern Asia served as the major source for H9N2 gene segments in the Middle East and Central Asia and that in this geographic region within-country evolution played a more important role in shaping viral genetic diversity than migration between countries. The genetic variability identified among the H9N2 viruses was associated with specific amino acid substitutions that are believed to result in increased transmissibility in mammals, as well as resistance to antiviral drugs. Our study highlights the need to constantly monitor the evolution of H9N2 viruses in poultry to better understand the potential risk to human health posed by these viruses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.