Evidence map›Paper›PMID 21679262›Full record

Trial reportThe American journal on addictions

Psychiatric and substance use disorders among methadone maintenance patients with chronic hepatitis C infection: effects on eligibility for hepatitis C treatment.

Steven L Batki, Kelly M Canfield, Robert Ploutz-Snyder

Erratum issuedOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Steven L BatkiDepartment of Psychiatry, University of California, San Francisco, USA. steven.batki@ucsf.edu
Kelly M Canfield
Robert Ploutz-Snyder
SUNY Upstate Medical University · USUniversities Space Research Association · USUniversity of California, San Francisco · US

Funding

Improving Hepatitis C Treatment in Injection Drug UsersR01DA016764 · NIDA · UPSTATE MEDICAL UNIVERSITY · PI BATKI, STEVEN L · 2003 to 2007
$3.5M
NIDA NIH HHS R01 DA 016764NIDA NIH HHS R01 DA016764
6 · The paper itself

Abstract

We set out to describe the prevalence and severity of psychiatric and substance use disorders (SUDs) in methadone maintenance treatment (MMT) patients with chronic hepatitis C virus (HCV) infection and to measure the impact on HCV-treatment eligibility. Psychiatric disorders, SUDs, and HCV-treatment eligibility were assessed in 111 MMT patients prior to a controlled trial of HCV treatment. Lifetime and current diagnosis rates, respectively, were: any non-SUD Axis I disorder: 82% and 57%, any mood disorder: 67% and 35%, any anxiety disorder: 63% and 22%, any psychotic disorder: 11% and 9%. Antisocial personality disorder was present in 40%. A total of 56% met criteria for current SUDs. A total of 66% received psychiatric medications prior to HCV treatment; over half were receiving antidepressants. Despite psychiatric and substance use comorbidity, only 15% of patients were ineligible for HCV treatment: 10% due to failure to complete the evaluation, and 5% due to psychiatric severity. Substance use did not lead to ineligibility in any participant. Multiple logistic regression showed the Beck Depression Inventory contributed significantly to predicting HCV treatment eligibility. Most MMT patients were eligible [corrected] for HCV treatment despite current SUD and non-SUD diagnoses. Depression severity may be a more significant predictor of HCV treatment eligibility than is substance use.

Indexed as

Eligibility DeterminationHepatitis C, ChronicMental DisordersMethadoneSubstance Abuse, IntravenousAdultAnalgesics, OpioidAntiviral AgentsComorbidityDepressionFemaleHepacivirusHumansMaleMiddle AgedOpiate Substitution TreatmentAnalgesics, OpioidAntiviral AgentsMethadonePsychotropic Drugs

Identifiers

PMID21679262
PMCPMC4651620
OpenAlexW1886858294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.