ArticleMicroscopy research and technique2011
Transmission electron microscopy as a tool to image bioinorganic nanohybrids: the case of phage-gold nanocomposites.
Article in Microscopy research and technique, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Article
- Exosome-Like Nanoparticles from Indonesian Red and Emprit Ginger Varieties Suppress LPS-Induced IL-6 Production in RAW 264.7 Macrophages.Advanced pharmaceutical bulletin · 2025Article
- Revisiting sodium phosphotungstate and ammonium molybdate as nonradioactive negative-staining agents for single-particle analysis.Acta crystallographica. Section F, Structural biology communications · 2024Article
- Phage cocktail amikacin combination as a potential therapy for bacteremia associated with carbapenemase producing colistin resistant Klebsiella pneumoniae.Scientific reports · 2024Article
- Article
- An Observation of a Very High Swelling of Bromovirus Members at Specific Ionic Strengths and pH.Viruses · 2023Article
- Food-Grade Quercetin-Loaded Nanoemulsion Ameliorates Effects Associated with Parkinson's Disease and Cancer: Studies Employing a TransgenicAntioxidants (Basel, Switzerland) · 2022Article
- Nanoparticles Influence Lytic Phage T4-like Performance In Vitro.International journal of molecular sciences · 2022Article
- X-ray Ptychography Imaging of Human Chromosomes After Low-dose Irradiation.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021Article
- pH-Independent Dissolution and Enhanced Oral Bioavailability of Aripiprazole-Loaded Solid Self-microemulsifying Drug Delivery System.AAPS PharmSciTech · 2021Article
- Ultra structural characteristics of methicillin resistantIranian journal of basic medical sciences · 2019Article
- Variations on Negative Stain Electron Microscopy Methods: Tools for Tackling Challenging Systems.Journal of visualized experiments : JoVE · 2018Article
- Identification of Novel Short BaTiOACS applied materials & interfaces · 2016Article
- Phage as a Genetically Modifiable Supramacromolecule in Chemistry, Materials and Medicine.Accounts of chemical research · 2016Article
- Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo.Theranostics · 2016Article
- Green Synthesis of Metallic Nanoparticles via Biological Entities.Materials (Basel, Switzerland) · 2015Review
- CaJournal of materials chemistry. B · 2015Article
- Phage as a template to grow bone mineral nanocrystals.Methods in molecular biology (Clifton, N.J.) · 2014Article
- Controlled alignment of filamentous supramolecular assemblies of biomolecules into centimeter-scale highly ordered patterns by using nature-inspired magnetic guidance.Angewandte Chemie (International ed. in English) · 2013Article
- Bacteriophage bionanowire as a carrier for both cancer-targeting peptides and photosensitizers and its use in selective cancer cell killing by photodynamic therapy.Small (Weinheim an der Bergstrasse, Germany) · 2013Article
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3 authors.
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Abstract
In recent years, bioinorganic nanohybrids composed of biological macromolecules and functional inorganic nanomaterials have revealed many unique properties that show promise for the future. Transmission electron microscopy (TEM) is a popular and relatively simple tool that can offer a direct visualization of the nanomaterials with high resolutions. When TEM is applied to visualize bioinorganic nanohybrids, a treatment of negative staining is necessary due to the presence of biological molecules in the nanohybrids except for those with densely packed inorganic materials. However, the conventional negative-staining procedure for regular biological samples cannot be directly applied to such bioinorganic nanohybrids. To image a specific bioinorganic nanohybrid, negative-staining factors such as negative stain type, working pH, staining time, and drying method, should be identified. Currently, no detailed studies have been done to investigate how to adjust negative-staining factors based on specific bioinorganic nanohybrids. In this study, bacteriophage-gold nanoparticle hybrids were chosen as a model to systematically study the effects of each factor on the negative staining of the nanohybrids. The best staining conditions for gold nanoparticle-phage nanohybrids were obtained and the effects of each factor on the negative staining of general nanohybrids were discussed. This work indicates that with proper staining it is possible to use TEM to visualize directly both biological and inorganic components without introducing any artifact.
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