ReviewPediatric radiology2011
Paediatric MRI under sedation: is it necessary? What is the evidence for the alternatives?
Review in Pediatric radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
91 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Chloral hydrate as a sedating agent for neurodiagnostic procedures in children.The Cochrane database of systematic reviews · 2021Pooled it
- Challenges and opportunities for neuroimaging in young patients with traumatic brain injury: a coordinated effort towards advancing discovery from the ENIGMA pediatric moderate/severe TBI group.Brain imaging and behavior · 2021Pooled it
- Non-pharmacological strategies to obtain usable magnetic resonance images in non-sedated infants: Systematic review and meta-analysis.International journal of nursing studies · 2020Pooled it
- Chloral hydrate as a sedating agent for neurodiagnostic procedures in children.The Cochrane database of systematic reviews · 2017Pooled it
- Scandinavian guidelines for initial management of minor and moderate head trauma in children.BMC medicine · 2016Guideline
- Using audiovisual intervention to reduce anxiety and improve image quality in pediatric magnetic resonance imaging.Pediatric radiology · 2025Trial
- Comparing a Virtual Reality-Based Simulation App (VR-MRI) With a Standard Preparatory Manual and Child Life Program for Improving Success and Reducing Anxiety During Pediatric Medical Imaging: Randomized Clinical Trial.Journal of medical Internet research · 2021Trial
- Development, validation, and pilot MRI safety study of a high-resolution, open source, whole body pediatric numerical simulation model.PloS one · 2021Trial
- [Application of vacuum stretcher combined with feeding in cranial magnetic resonance imaging examination for neonates: a prospective randomized controlled study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Trial
- Does preparation of children before MRI reduce the need for anesthesia? Prospective randomized control trial.Pediatric radiology · 2016Trial
- A randomized controlled trial: child life services in pediatric imaging.Pediatric radiology · 2014Trial
- Comparison between intranasal dexmedetomidine and intranasal ketamine as premedication for procedural sedation in children undergoing MRI: a double-blind, randomized, placebo-controlled trial.Journal of anesthesia · 2014Trial
- Use of animated cartoons with children's songs to increase compliance with ultrasonography in young children.Yonsei medical journal · 2013Trial
- Feasibility, image quality, and analytic usability of mobile 64 mT ultra-low-field MRI for infant brain imaging at 3 and 12 months in southern Malawi.Journal of magnetic resonance open · 2026Article
- Streamlining pediatric musculoskeletal infection workup: the why, what, and how of rapid MRI protocols.Pediatric radiology · 2026Review
- Routine MRI in Pediatric Scoliosis: A Narrative Review of Risk-Stratified and Abbreviated Protocols.Orthopedic research and reviews · 2026Review
- Magnetic Resonance Cholangiopancreatography for Cholangiopathy After Pediatric Liver Transplantation: A Retrospective Analysis and Correlation With Clinical Outcome.Pediatric transplantation · 2025Article
- Accelerated brain magnetic resonance imaging with deep learning reconstruction: a comparative study on image quality in pediatric neuroimaging.Pediatric radiology · 2025Article
- A 60-channel high-density flexible receive array for pediatric abdominal MRI.Magnetic resonance in medicine · 2025Article
- Deep learning MR reconstruction in knees and ankles in children and young adults. Is it ready for clinical use?Skeletal radiology · 2025Article
31 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
To achieve diagnostic images during MRI examinations, small children need to lie still to avoid movement artefact. To reduce patient motion, obviate the need for voluntary immobilisation or breath-holding and therefore obtain high-quality images, MRI of infants is frequently carried out under sedation or general anaesthesia, but this is not without risk and expense. However, many other techniques are available for preparing children for MRI, which have not been fully evaluated. Here, we evaluate the advantages and disadvantage of sedation and anaesthesia for MRI. We then evaluate the alternatives, which include neonatal comforting techniques, sleep manipulation, and appropriate adaptation of the physical environment. We summarize the evidence for their use according to an established hierarchy. Lastly, we discuss several factors that will influence the choice of imaging preparation, including patient factors, imaging factors and service provision. The choice of approach to paediatric MRI is multi-factorial, with limited scientific evidence for many of the current approaches. These considerations may enable others to image children using MRI under different circumstances.
Indexed as
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21678113What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.