ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2011
Driving simulator performance remains impaired in patients with severe OSA after CPAP treatment.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 47 citations in OpenAlex.
- Quetiapine modestly improves sleep and breathing but impairs next-day performance in people with obstructive sleep apnea and difficulty maintaining sleep: a randomized controlled trial.Annals of the American Thoracic Society · 2026Trial
- Prevalence of Obstructive Sleep Apnea and Adherence to CPAP for TAXI Drivers.Clocks & sleep · 2026Article
- Protocol for a pilot hybrid type I effectiveness-implementation study to improve help-seeking for sleep disorders in the future healthcare workforce: The Sleep Check Before Shift Work trial.Sleep advances : a journal of the Sleep Research Society · 2025Article
- European Union directive 2014/85/EU on driver licensing in obstructive sleep apnoea: early experiences with its application in the UK.Breathe (Sheffield, England) · 2016Article
- Sleep apnoea and driving risk: the need for regulation.European respiratory review : an official journal of the European Respiratory Society · 2015Review
- Effects of obstructive sleep apnea on sleep quality, cognition, and driving performance in patients with cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2015Article
- The impact of sleep on soldier performance.Current psychiatry reports · 2014Review
- Association of sleep habits with accidents and near misses in United States transportation operators.Journal of occupational and environmental medicine · 2014Article
- Sleep apnea and occupational accidents: Are oral appliances the solution?Indian journal of occupational and environmental medicine · 2014Review
- Epilepsy and driving: potential impact of transient impaired consciousness.Epilepsy & behavior : E&B · 2014Review
- Obstructive sleep apnea in North American commercial drivers.Industrial health · 2014Review
- An official American Thoracic Society Clinical Practice Guideline: sleep apnea, sleepiness, and driving risk in noncommercial drivers. An update of a 1994 Statement.American journal of respiratory and critical care medicine · 2013Review
- Sleep disorders as a cause of motor vehicle collisions.International journal of preventive medicine · 2013Article
- The public health burden of obstructive sleep apnea.Sleep science (Sao Paulo, Brazil)Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo assess the effectiveness of CPAP treatment in improving 90-minute driving simulator performance in severe OSA patients compared to age/gender matched controls.
designDriving simulator performance was assessed at baseline and 3 months later, with OSA patients treated with CPAP during the interval.
settingUniversity Teaching Hospital.
participantsPatients with severe OSA (n = 11) and control subjects without OSA (n = 9).
interventionsCPAP MEASUREMENTS AND
resultsSimulator driving parameters of steering deviation, braking reaction time and crashes were measured at baseline and ∼3 months follow-up. At baseline, OSA subjects demonstrated significantly greater steering deviation compared to controls (mean [95% CI], OSA group, 49.9 cm [43.7 to 56.0 cm] vs control group, 34.9 cm [28.1 to 41.7 cm], p = 0.003). Following ∼3 months of CPAP treatment (mean ± SD 6.0 ± 1.4 h/night), steering deviation in OSA subjects improved by an average of 3.1 cm (CI, 1.4 to 4.9), p < 0.001, while no significant steering changes were observed in the control group. Despite the improvement, steering deviation in the OSA group remained significantly higher than in controls (OSA group, 46.7 cm [CI, 40.6 to 52.8 cm] vs control group, 36.1 cm [CI, 29.3 to 42.9 cm], p = 0.025).
conclusionsWhile driving simulator performance improved after ∼3 months of CPAP treatment with high adherence in patients with severe OSA, performance remained impaired compared to control subjects. These results add to the growing body of evidence that some neurobehavioral deficits in patients with severe OSA are not fully reversed by treatment. Further studies are needed to assess causes of residual driving simulator impairment and to determine whether this is associated with persistent elevated real-life accident risk.
trial registrationData presented in this manuscript was collected as part of a clinical trial "Experimental Investigations of Driving Impairment in Obstructive Sleep Apnoea" ACTRN12610000009011, http://www.anzctr.org.au/trial_view.aspx?ID=334979
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