Evidence map›Paper›PMID 21677686›Full record

ReviewNature reviews. Microbiology2011

Host factors involved in retroviral budding and release.

Juan Martin-Serrano, Stuart J D Neil

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Functional 20S Proteasomes in Retroviruses: Evidence in Favor.International journal of molecular sciences · 2024
    Article
  6. Review
  7. Article
  8. Structural Relationships to Efficacy for Prazole-Derived Antivirals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Plasmacytoid dendritic cells in the eye.Progress in retinal and eye research · 2021
    Review
  20. Review

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Juan Martin-SerranoDepartment of Infectious Diseases, Second Floor Borough Wing, Guy's Hospital, London, SE1 9RT, UK. juan.martin_serrano@kcl.ac.uk
Stuart J D Neil

Funding

Medical Research Council G0801937Medical Research Council G0802777Wellcome Trust WT082274MAWellcome Trust WT093056MA
6 · The paper itself

Abstract

The plasma membrane is the final barrier that enveloped viruses must cross during their egress from the infected cell. Here, we review recent insights into the cell biology of retroviral assembly and release; these insights have driven a new understanding of the host proteins, such as the ESCRT machinery, that are used by retroviruses to promote their final separation from the host cell. We also review antiviral host factors such as tetherin, which can directly inhibit the release of retroviral particles. These studies have illuminated the role of the lipid bilayer as the unexpected target for virus restriction by the innate immune response.

Indexed as

Antigens, CDAntiviral AgentsBone Marrow Stromal Antigen 2Cell LineEndosomal Sorting Complexes Required for TransportGene Expression Regulation, ViralGPI-Linked ProteinsHIV-1HumansRetroviridaeVirus AssemblyVirus ReleaseAntigens, CDAntiviral AgentsBone Marrow Stromal Antigen 2BST2 protein, humanEndosomal Sorting Complexes Required for TransportGPI-Linked Proteins

Identifiers

PMID21677686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.