ArticleBMC research notes2011
Lipid profiles of female and male Drosophila.
Article in BMC research notes, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 59 citations in OpenAlex.
- Sex-biased expression of enteroendocrine cell-derived hormones contributes to higher fat storage ineLife · 2026Article
- Effect of Aerobic Exercise and a Diet Supplementation with Linoleic Acid on Metabolic Parameters inBiology · 2026Article
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- Germline proliferation trades off with lipid metabolism inEvolution letters · 2024Article
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- The isothermal Boltzmann-Gibbs entropy reduction affects survival of the fruit fly Drosophila melanogaster.Scientific reports · 2023Article
- Spenito-dependent metabolic sexual dimorphism intrinsic to fat storage cells.bioRxiv : the preprint server for biology · 2023Article
- A protein restricted diet induces a stable increased fat storage phenotype in flies.Toxicology reports · 2023Article
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- Rosy Beginnings: Studying Peroxisomes inFrontiers in cell and developmental biology · 2020Review
- The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster.Scientific reports · 2018Article
- Investigation of the phosphatidylserine binding properties of the lipid biosensor, Lactadherin C2 (LactC2), in different membrane environments.Journal of bioenergetics and biomembranes · 2018Article
- Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults.BMC genomics · 2017Article
- Beyond antioxidant genes in the ancient Nrf2 regulatory network.Free radical biology & medicine · 2015Article
- As the fat flies: The dynamic lipid droplets of Drosophila embryos.Biochimica et biophysica acta · 2015Review
- Article
- Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogaster.Aging cell · 2014Article
- Spermidine feeding decreases age-related locomotor activity loss and induces changes in lipid composition.PloS one · 2014Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundD. melanogaster is increasingly used as a lipid metabolism model, but the D. melanogaster metabolome is not well studied. A number of studies strongly suggest that lipid metabolism is linked to sexual behavior and gametogenesis.
findingsWe determined the levels of 400 different lipids in the non-gonadal soma of D. melanogaster females and males. We found higher levels of saturated cholesterol esters and lysophosphatidylcholine in males, and higher levels of polyunsaturated cholesterol esters in females. We also determined the levels of these lipids in females and males without a germline to determine if the absence of gamete "sinks" for metabolic products, such as yolk and lipid deposits in eggs, altered somatic lipid profiles. We observed little change in lipid profiles between these samples.
conclusionsOverall lipid compositions are similar between the sexes, although there are differences in saturation states of two lipid classes, where saturated fatty acids were male-biased and polyunsaturated fatty acids were female-biased. The presence of a germline did not significantly influence lipid profiles, raising the possibility that germline-dependent changes in metabolic gene expression patterns serve a homeostatic purpose.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.