ArticleArthritis research & therapy2011
Predictors for pathologically confirmed aortitis after resection of the ascending aorta: a 12-year Danish nationwide population-based cross-sectional study.
Article in Arthritis research & therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 58 citations in OpenAlex.
- Undiagnosed Thoracic Aortic Aneurysms: Prevalence, Risk Factors, Screening Modalities.Deutsches Arzteblatt international · 2026Review
- Inflammatory Aortopathies in Rheumatic Diseases: A State-of-the-Art Review.Diagnostics (Basel, Switzerland) · 2026Review
- A Narrative Review of Biomarkers and Imaging in the Diagnosis of Acute Aortic Syndrome.Diagnostics (Basel, Switzerland) · 2025Review
- Aortitis Increases the Risk of Surgical Complications and Re-Operations After Major Aortic Surgery.Journal of cardiovascular development and disease · 2024Article
- Multi-Modality Imaging in Vasculitis.Diagnostics (Basel, Switzerland) · 2024Review
- A Cautionary Note on Pembrolizumab use in Patients with Ascending Aortic Aneurysms.European journal of case reports in internal medicine · 2024Article
- Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease.International journal of molecular sciences · 2023Review
- The epidemiology of pathologically confirmed clinically isolated aortitis: a North American population-based study.Clinical and experimental rheumatology · 2023Article
- Long-Term Clinical and Radiographic Outcomes in Patients With Clinically Isolated Aortitis.ACR open rheumatology · 2022Article
- Clinically isolated aortitis: imaging features and clinical outcomes: comparison with giant cell arteritis and giant cell aortitis.The international journal of cardiovascular imaging · 2021Article
- Spontaneous resolution of idiopathic aortitis and pitfalls in diagnosis.Journal of vascular surgery cases and innovative techniques · 2019Article
- Diagnosis and differential diagnosis of large-vessel vasculitides.Rheumatology international · 2019Review
- Characteristics and outcomes in a prospective cohort of patients with histologically diagnosed aortitis.Rheumatology advances in practice · 2019Article
- Aneurysm of the ascending aorta in systemic lupus erythematosus: Case report and review of the literature.European journal of rheumatology · 2017Article
- Plasmacytic Aortitis with Occlusion of the Right Coronary Artery.The American journal of case reports · 2016Article
- Anemia in a middle aged female with aortitis: a case report.BMC research notes · 2015Article
- Isolated aortitis: a rare cause of febrile illness.BMJ case reports · 2015Article
- Pulmonary oedema in the emergency room: what is hidden beyond an apparently common presentation.BMJ case reports · 2014Article
- [Inflammatory aortic diseases].Der Internist · 2013Review
- CMR in inflammatory vasculitis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2012Review
Corrections and comments
- Commented on by
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAssessing the prevalence of, and predictors for, pathologically-confirmed inflammation of the aorta in Denmark, using a nationwide population-based study design.
methodsWe identified all adults with first-time surgery on the ascending aorta between January 1, 1997 and March 1, 2009 in Denmark. Presence of aortic inflammation was ascertained through linkage to a nationwide pathology registry. We used logistic regression to compute prevalence odds ratios (ORs) for sex, age at surgery, cardiovascular risk factors, cancer, connective tissue disease, and infectious diseases associated with the presence of aortitis.
resultsA total of 1,210 adults underwent resection of the ascending aorta, of who 610 (50.4%) had tissue submitted for pathological examination. Aortitis was found in 37 (6.1%) patients whose tissue was examined. Ten of the 37 patients were diagnosed with conditions known to be associated with aortitis or aortic aneurysm: five patients with temporal arteritis, one with Crohn's disease, one with rheumatoid arthritis, one with systemic lupus erythematosus, one with infectious aortitis, and one with Marfan's disease. Twenty-seven patients had idiopathic aortitis. Predictors of aortitis included history of connective tissue disease (adjusted OR 4.7, 95% confidence interval (CI) 1.6, 13.6), diabetes (OR 5.2, 95% CI 0.9, 29.7), advanced age (> 67 years OR 2.5, 95% CI 0.8, 7.6), and aortic valve pathology (OR 2.3, 95% CI 1.1, 4.9).
conclusionsAortitis was present in 6.1% of adults in Denmark who had pathological examination after resection of the ascending aorta. Predictors of inflammation included connective tissue disease, diabetes, advanced age, and aortic valve pathology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.