Evidence map›Paper›PMID 21674616›Full record

ArticleMagnetic resonance in medicine2012

Improved method for quantification of regional cardiac function in mice using phase-contrast MRI.

Erica Dall'Armellina, Bernd A Jung, Craig A Lygate, Stefan Neubauer, Michael Markl, Jürgen E Schneider

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Novel insight into the detailed myocardial motion and deformation of the rodent heart using high-resolution phase contrast cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2013
    Article
  8. A quantitative comparison of regional myocardial motion in mice, rabbits and humans using in-vivo phase contrast CMR.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2012
    Article
  9. Comprehensive cardiovascular magnetic resonance of myocardial mechanics in mice using three-dimensional cine DENSE.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erica Dall'ArmellinaDepartment of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
Bernd A Jung
Craig A Lygate
Stefan Neubauer
Michael Markl
Jürgen E Schneider

Funding

British Heart Foundation BS/06/001British Heart Foundation FS/11/50/29038British Heart Foundation R6/10/002/28187British Heart Foundation RG/10/002/28187Wellcome Trust 075491/Z/04Wellcome Trust 090532
6 · The paper itself

Abstract

Phase-contrast magnetic resonance imaging is a technique that allows for characterization of regional cardiac function and for measuring transmural myocardial velocities in human hearts with high temporal and spatial resolution. The application of this technique (also known as tissue phase mapping) to murine hearts has been very limited so far. The aim of our study was to implement and to optimize tissue phase mapping for a comprehensive assessment of murine transmural wall motion. Baseline values for regional motion patterns in mouse hearts, based on the clinically used American Heart Association's 17-segment model, were established, and a detailed motion analysis of mouse heart for the entire cardiac cycle (including epicardial and endocardial motion patterns) is provided. Black-blood contrast was found to be essential to obtain reproducible velocity encoding. Tissue phase mapping of the mouse heart permits the detailed assessment of regional myocardial velocities. While a proof-of-principle application in a murine ischemia-reperfusion model was performed, future studies are warranted to assess its potential for the investigation of systolic and diastolic functions in genetically and surgically manipulated mouse models of human heart disease.

Indexed as

Contrast MediaAnimalsArtifactsBlood Flow VelocityFemaleHeartHumansImage EnhancementImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiceMice, Inbred C57BLMyocardial ContractionMyocardial Reperfusion InjurySensitivity and SpecificityContrast Media

Identifiers

PMID21674616
PMCPMC3378699

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.