Evidence map›Paper›PMID 21674021›Full record

ArticleInternational journal of nanomedicine2011

Ibuprofen-loaded poly(lactic-co-glycolic acid) films for controlled drug release.

Jianmei Pang, Yuxia Luan, Feifei Li, Xiaoqing Cai, Jimin Du, Zhonghao Li

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Localized and targeted delivery of NSAIDs for treatment of inflammation: A review.Experimental biology and medicine (Maywood, N.J.) · 2019
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianmei PangSchool of Pharmaceutical Science, Shandong University, Jinan, Shandong Province, PR China.
Yuxia Luan
Feifei Li
Xiaoqing Cai
Jimin Du
Zhonghao Li

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ibuprofen- (IBU) loaded biocompatible poly(lactic-co-glycolic acid) (PLGA) films were prepared by spreading polymer/ibuprofen solution on the nonsolvent surface. By controlling the weight ratio of drug and polymer, different drug loading polymer films can be obtained. The synthesized ibuprofen-loaded PLGA films were characterized with scanning electron microscopy, powder X-ray diffraction, and differential scanning calorimetry. The drug release behavior of the as-prepared IBU-loaded PLGA films was studied to reveal their potential application in drug delivery systems. The results show the feasibility of the as-obtained films for controlling drug release. Furthermore, the drug release rate of the film could be controlled by the drug loading content and the release medium. The development of a biodegradable ibuprofen system, based on films, should be of great interest in drug delivery systems.

Indexed as

Calorimetry, Differential ScanningDelayed-Action PreparationsDrug Delivery SystemsIbuprofenKineticsLactic AcidMicroscopy, Electron, ScanningPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerPowder DiffractionDelayed-Action PreparationsIbuprofenLactic AcidPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymercontrolled releasefilmsibuprofenpoly(lactic-co-glycolic acid)

Identifiers

PMID21674021
PMCPMC3107723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.