ArticleKidney international2011
Hypertension as a mitochondrial and metabolic disease.
Article in Kidney international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet.Theranostics · 2018Trial
- Mitochondrial Dysfunction in the Cardiovascular Disease Continuum: Problems of Studying the Progression During the Follow-Up of the Pathologies.International journal of molecular sciences · 2025Review
- Human plasma metabolomics reveals metabolic targets for intervention in salt-sensitive hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Identification of an Exosomal miRNA Signature in Newly Diagnosed Essential Hypertensive Adults.British journal of biomedical science · 2025Article
- Transcriptomic changes in glomeruli in response to a high salt challenge in the Dahl SS rat.Physiological genomics · 2024Article
- Fumarate and its downstream signalling pathways in the cardiorenal system: Recent insights and novel expositions in the etiology of hypertension.European journal of pharmacology · 2023Review
- Study design, general characteristics of participants, and preliminary findings from the metabolome, microbiome, and dietary salt intervention study (MetaSalt).Chronic diseases and translational medicine · 2021Article
- Fumarate exerted an antihypertensive effect and reduced kidney injury molecule (KIM)-1 expression in deoxycorticosterone acetate-salt hypertension.Clinical and experimental hypertension (New York, N.Y. : 1993) · 2021Article
- Renal metabolism and hypertension.Nature communications · 2021Review
- Mitochondrial tRNA Mutations Associated With Essential Hypertension: From Molecular Genetics to Function.Frontiers in cell and developmental biology · 2020Review
- Fumarase Overexpression Abolishes Hypertension Attributable to endothelial NO synthase Haploinsufficiency in Dahl Salt-Sensitive Rats.Hypertension (Dallas, Tex. : 1979) · 2019Article
- Elevation of fumarase attenuates hypertension and can result from a nonsynonymous sequence variation or increased expression depending on rat strain.Physiological genomics · 2017Article
- Emerging roles of tRNA in adaptive translation, signalling dynamics and disease.Nature reviews. Genetics · 2015Review
- Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for young hypertensive men.Analytica chimica acta · 2015Article
- Analysis of metabolites in plasma reveals distinct metabolic features between Dahl salt-sensitive rats and consomic SS.13(BN) rats.Biochemical and biophysical research communications · 2014Article
- Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats.Physiological genomics · 2014Article
- Ultrastructure of mitochondria and the endoplasmic reticulum in renal tubules of Dahl salt-sensitive rats.American journal of physiology. Renal physiology · 2014Article
- Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence.Hypertension (Dallas, Tex. : 1979) · 2014Article
- Article
- Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat.Hypertension (Dallas, Tex. : 1979) · 2013Article
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
Abstract
The molecular pathophysiology of hypertension is probably like a jigsaw puzzle of different but overlapping sets of factors and pathways that vary from one patient or one group of patients to another. Mitochondrial and metabolic abnormalities could be crucial pieces of this puzzle.
Indexed as
Identifiers
21673736What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.