ArticleJournal of visualized experiments : JoVE2011
Fabrication of electrochemical-DNA biosensors for the reagentless detection of nucleic acids, proteins and small molecules.
Article in Journal of visualized experiments : JoVE, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The trial behind it
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Who cites it
13 citing papers in PubMed.
- Amplification-Free Detection of MiRNA Signatures in Milk: A Noninvasive Sensing Approach for Early Diagnosis of Bovine Mastitis.ACS measurement science au · 2026Article
- Advanced Nanomaterial-Based Electrochemical Biosensing of Loop-Mediated Isothermal Amplification Products.Biosensors · 2025Article
- Electrochemical Aptamer-Based Biosensor for Detecting Pap31, a Biomarker for Carrion's Disease.Sensors (Basel, Switzerland) · 2024Article
- IFN-γ and IL-10 Immunosensor with Vertically Aligned Carbon Nanotube Interdigitated Electrodes toward Pen-Side Cattle Paratuberculosis Monitoring.Global challenges (Hoboken, NJ) · 2024Article
- Rapid and Quantitative Detection of Lung Cancer Biomarker ENOX2 Using a Novel Aptamer in an Electrochemical DNA-Based (E-DNA) Biosensor.Biosensors · 2023Article
- Electrochemical DNA Biosensor That Detects Early Celiac Disease Autoantibodies.Sensors (Basel, Switzerland) · 2021Article
- Opportunities, Challenges, and Prospects in Electrochemical Biosensing of Circulating Tumor DNA and its Specific Features.Sensors (Basel, Switzerland) · 2019Review
- Electrochemical Aptamer-Based Sensors for Rapid Point-of-Use Monitoring of the Mycotoxin Ochratoxin A Directly in a Food Stream.Molecules (Basel, Switzerland) · 2018Article
- Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors.Scientific reports · 2017Article
- Point-of-care (POC) devices by means of advanced MEMS.Talanta · 2015Review
- Nanostructured gold dsDNA sensor for early detection of breast cancer by beta protein 1 (BPJournal of electroanalytical chemistry (Lausanne, Switzerland) · 2015Article
- Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor.The Analyst · 2013Article
- Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range.Angewandte Chemie (International ed. in English) · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
As medicine is currently practiced, doctors send specimens to a central laboratory for testing and thus must wait hours or days to receive the results. Many patients would be better served by rapid, bedside tests. To this end our laboratory and others have developed a versatile, reagentless biosensor platform that supports the quantitative, reagentless, electrochemical detection of nucleic acids (DNA, RNA), proteins (including antibodies) and small molecules analytes directly in unprocessed clinical and environmental samples. In this video, we demonstrate the preparation and use of several biosensors in this "E-DNA" class. In particular, we fabricate and demonstrate sensors for the detection of a target DNA sequence in a polymerase chain reaction mixture, an HIV-specific antibody and the drug cocaine. The preparation procedure requires only three hours of hands-on effort followed by an overnight incubation, and their use requires only minutes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.