Evidence map›Paper›PMID 21673581›Full record

ArticleGenetics in medicine : official journal of the American College of Medical Genetics2011

Consideration of patient preferences and challenges in storage and access of pharmacogenetic test results.

Susanne B Haga, Kensaku Kawamoto, Robert Agans, Geoffrey S Ginsburg

Abstract read
In one paragraph

Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system.Genetics in medicine : official journal of the American College of Medical Genetics · 2018
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Delivering pharmacogenetic testing in a primary care setting.Pharmacogenomics and personalized medicine · 2013
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susanne B HagaInstitute for Genome Sciences & Policy and Sanford School of Public Policy, Duke University, Durham, NC 27708, USA. susanne.haga@duke.edu
Kensaku Kawamoto
Robert Agans
Geoffrey S Ginsburg

Funding

Pharmacogenetic Testing: Challenges of Clinical IntegrationR01GM081416 · NIGMS · DUKE UNIVERSITY · PI HAGA, SUSANNE · 2008 to 2018
$4.6M
NIGMS NIH HHS R01 GM081416NIGMS NIH HHS R01 GM081416-01A1
6 · The paper itself

Abstract

purposePharmacogenetic testing is one of the primary drivers of personalized medicine. The use of pharmacogenetic testing may provide a lifetime of benefits through tailoring drug dosing and selection of multiple medications to improve therapeutic outcomes and reduce adverse responses. We aimed to assess public interest and concerns regarding sharing and storage of pharmacogenetic test results that would facilitate the reuse of pharmacogenetic data across a lifetime of care.

methodsWe conducted a random-digit-dial phone survey of a sample of the US public.

resultsWe achieved an overall response rate of 42% (n = 1139). Most respondents indicated that they were extremely or somewhat comfortable allowing their pharmacogenetic test results to be shared with other doctors involved in their care management (90% ± 2.18%); significantly fewer respondents (74% ± 3.27%) indicated that they were extremely or somewhat comfortable sharing results with their pharmacist (P < 0.0001).

conclusionPatients, pharmacists, and physicians will all be critical players in the pharmacotherapy process. Patients are supportive of sharing pharmacogenetic test results with physicians and pharmacists and personally maintaining their test results. However, further study is needed to understand which options are needed for sharing, appropriate storage, and patient education about the relevance of pharmacogenetic test results to promote consideration of this information by other prescribing practitioners.

Indexed as

Information Storage and RetrievalMedical Records Systems, ComputerizedPatient PreferenceAdolescentAdultFemaleHumansMaleMiddle AgedPharmacogeneticsPublic OpinionSurveys and QuestionnairesYoung Adult

Identifiers

PMID21673581
PMCPMC3731746

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.