ArticleThe Plant cell2011
The MYB80 transcription factor is required for pollen development and the regulation of tapetal programmed cell death in Arabidopsis thaliana.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers.
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Who cites it
150 citing papers in PubMed.
- Beyond degradation: Dissecting autophagy-protease relationships in plant reproduction.Plant reproduction · 2026Review
- Genome-Wide Study of MYB Transcription Factors in Maize and Their Essential Roles in Male Fertility and Other Biological Processes.International journal of molecular sciences · 2026Article
- Deciphering the genetic basis of wheat germination under ZnO nano priming and drought stress through integrated QTL mapping and network analyses.BMC plant biology · 2026Article
- Network ontology transcript annotation identifies genetic signals underlying sex determination.Scientific reports · 2026Article
- Genome-wide identification, structural characterization, and gene expression analysis of the MYB transcription factor family in faba bean (Vicia faba L.).BMC plant biology · 2026Article
- Analysis of the aspartic protease gene family inFrontiers in plant science · 2026Article
- Single-Cell Transcriptome Atlas and Dynamic Regulatory Mechanisms of Anther Development in Alfalfa (Medicago sativa L.).Plant biotechnology journal · 2025Article
- The basic helix-loop-helix (bHLH) transcription factor DTT1 is part of a paired key that unlocks the tapetum transition in barley anther development.The Plant cell · 2025Article
- Genome-Wide Analysis of the Common Fig (Ficus carica L.) R2R3-MYB Genes Reveals Their Structure, Evolution, and Roles in Fruit Color Variation.Biochemical genetics · 2025Article
- Article
- Identity Transitions of Tapetum Phases: Insights into Vesicular Dynamics and in Mortem Support During Pollen Maturation.Plants (Basel, Switzerland) · 2025Review
- Exploration of the molecular mechanism behind a novel natural genic male-sterile mutation of 1205A in Brassica napus.BMC plant biology · 2025Article
- Regulatory analysis of root architectural and anatomical adaptation to nitrate and ammonium inFrontiers in plant science · 2025Article
- Unlocking male sterility in horticultural crops through gene editing technology for precision breeding applications: presentation of a case study in tomato.Frontiers in plant science · 2025Article
- Article
- Transcriptome Remodeling inPlants (Basel, Switzerland) · 2024Article
- Molecular mechanisms underlying the negative effects of transient heatwaves on crop fertility.Plant communications · 2024Review
- SlHB8 Is a Novel Factor in Enhancing Cold Resistance in Tomato Anthers by Modulating Tapetal Cell Death.International journal of molecular sciences · 2024Article
- MAPK20-mediated ATG6 phosphorylation is critical for pollen development inHorticulture research · 2024Article
- Identification of Genomic Regions for Traits Associated with Flowering in Cassava (Plants (Basel, Switzerland) · 2024Article
90 more citing papers are in PubMed but not listed here.
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Arabidopsis thaliana MYB80 (formerly MYB103) is expressed in the tapetum and microspores between anther developmental stages 6 and 10. MYB80 encodes a MYB transcription factor that is essential for tapetal and pollen development. Using microarray analysis of anther mRNA, we identified 404 genes differentially expressed in the myb80 mutant. Employing the glucocorticoid receptor system, the expression of 79 genes was changed when MYB80 function was restored in the myb80 mutant following induction by dexamethasone. Thirty-two genes were analyzed using chromatin immunoprecipitation, and three were identified as direct targets of MYB80. The genes encode a glyoxal oxidase (GLOX1), a pectin methylesterase (VANGUARD1), and an A1 aspartic protease (UNDEAD). All three genes are expressed in the tapetum and microspores. Electrophoretic mobility shift assays confirmed that MYB80 binds to all three target promoters, with the preferential binding site containing the CCAACC motif. TUNEL assays showed that when UNDEAD expression was silenced using small interfering RNA, premature tapetal and pollen programmed cell death occurred, resembling the myb80 mutant phenotype. UNDEAD possesses a mitochondrial targeting signal and may hydrolyze an apoptosis-inducing protein(s) in mitochondria. The timing of tapetal programmed cell death is critical for pollen development, and the MYB80/UNDEAD system may regulate that timing.
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