ArticleThe Plant cell2011
The Arabidopsis NAC transcription factor VNI2 integrates abscisic acid signals into leaf senescence via the COR/RD genes.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers, 1 of them a synthesis that pooled it.
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Who cites it
193 citing papers in PubMed, 1 synthesis or guideline pooled it, 391 citations in OpenAlex.
- Pooled it
- The NAC transcription factor BrrNAC082 positively mediates leaf senescence in Brassica rapa.The Plant journal : for cell and molecular biology · 2026Article
- From signals to solutions: stress-induced leaf senescence and synthetic biology and AI approaches for crop resilience.Molecular horticulture · 2026Review
- Regulatory Network of Leaf Senescence inInternational journal of molecular sciences · 2026Review
- DIVARICATA1 Promotes Leaf Degreening and Senescence in Arabidopsis.Plants (Basel, Switzerland) · 2026Article
- Transcriptome profiling reveals divergent response strategies in two olive cultivars with contrasting drought tolerance.Plant physiology · 2026Article
- Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- The NtBAG5-CaM complex integrates CaGM crops & food · 2025Article
- Dual roles of SmCLE25 peptide in regulating stresses response and leaf senescence.BMC plant biology · 2025Article
- XND1-centered network regulates salt tolerance by integrating root xylem plasticity and NaProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Identification of Salt Tolerance-RelatedPlants (Basel, Switzerland) · 2025Article
- NAC047/052/104 Synergistically Regulate the Dark-Induced Leaf Senescence in Non-Heading Chinese Cabbage.International journal of molecular sciences · 2025Article
- Transcriptomic and metabolomic analysis of yellow leaf mutant variation inFrontiers in plant science · 2025Article
- Altering cold-regulated gene expression decouples the salicylic acid-growth trade-off in Arabidopsis.The Plant cell · 2024Article
- Identification of a Novel GeneInternational journal of molecular sciences · 2024Article
- Identification of Novel Regulators of Leaf Senescence Using a Deep Learning Model.Plants (Basel, Switzerland) · 2024Article
- OsNAC103, a NAC Transcription Factor, Positively Regulates Leaf Senescence and Plant Architecture in Rice.Rice (New York, N.Y.) · 2024Article
- Hydrogen Peroxide Promotes Tomato Leaf Senescence by Regulating Antioxidant System and Hydrogen Sulfide Metabolism.Plants (Basel, Switzerland) · 2024Article
- Banana MaNAC1 activates secondary cell wall cellulose biosynthesis to enhance chilling resistance in fruit.Plant biotechnology journal · 2024Article
- Physiological and molecular characteristics associated with the anti-senescence inPhotosynthetica · 2024Article
133 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leaf aging is a highly regulated developmental process, which is also influenced profoundly by diverse environmental conditions. Accumulating evidence in recent years supports that plant responsiveness to abiotic stress is intimately related with leaf longevity. However, molecular mechanisms underlying the signaling crosstalks and regulatory schemes are yet unknown. In this work, we demonstrate that an abscisic acid (ABA)-responsive NAC transcription factor VND-INTERACTING2 (VNI2) integrates ABA-mediated abiotic stress signals into leaf aging by regulating a subset of COLD-REGULATED (COR) and RESPONSIVE TO DEHYDRATION (RD) genes. The VNI2 gene was induced by high salinity in an ABA-dependent manner. In addition, spatial and temporal expression patterns of the VNI2 gene are correlated with leaf aging and senescence. Accordingly, leaf aging was delayed in transgenic plants overexpressing the VNI2 gene but significantly accelerated in a VNI2-deficient mutant. The VNI2 transcription factor regulates the COR and RD genes by binding directly to their promoters. Notably, transgenic plants overexpressing the COR or RD genes exhibited prolonged leaf longevity. These observations indicate that the VNI2 transcription factor serves as a molecular link that integrates plant responses to environmental stresses into modulation of leaf longevity.
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