Evidence map›Paper›PMID 21671432›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2011

Beauty is skin deep: a surface monolayer perspective on nanoparticle interactions with cells and bio-macromolecules.

Krishnendu Saha, Avinash Bajaj, Bradley Duncan, Vincent M Rotello

Abstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 95 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Nanotherapeutics in autophagy: a paradigm shift in cancer treatment.Drug delivery and translational research · 2022
    Review
  7. Review
  8. Review
  9. Article
  10. Protein-Engineered Functional Materials.Advanced healthcare materials · 2019
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Control of nanoparticle penetration into biofilms through surface design.Chemical communications (Cambridge, England) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Krishnendu SahaDepartment of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA 01003, USA.
Avinash Bajaj
Bradley Duncan
Vincent M Rotello
University of Massachusetts Amherst · US

Funding

Recognition and Presentation of Alpha Helices using Nanoparticle ReceptorsR01GM077173 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ROTELLO, VINCENT M. · 2007 to 2018
$3.7M
Multiplexed Tracking of Nanoparticles using Laser Desorption/Ionization Mass SpecR21ES017871 · NIEHS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ROTELLO, VINCENT M., VACHET, RICHARD W · 2010 to 2011
$420k
Nanoparticle-Stabilized Capsules as Drug Delivery SystemsR21EB012246 · NIBIB · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ROTELLO, VINCENT M. · 2010 to 2011
$408k
NIBIB NIH HHS EB012246NIBIB NIH HHS R21 EB012246NIEHS NIH HHS ES017871NIEHS NIH HHS R21 ES017871NIGMS NIH HHS GM077173NIGMS NIH HHS R01 GM077173
6 · The paper itself

Abstract

Surface recognition of biosystems is a critical component in the development of novel biosensors and delivery vehicles, and for the therapeutic regulation of biological processes. Monolayer-protected nanoparticles present a highly versatile scaffold for selective interaction with bio-macromolecules and cells. Through the engineering of the monolayer surface, nanoparticles can be tailored for surface recognition of biomolecules and cells. This review highlights recent progress in nanoparticle-bio-macromolecule/cellular interactions, emphasizing the effect of the surface monolayer structure on the interactions with proteins, DNA, and cell surfaces. The extension of these tailored interactions to hybrid nanomaterials, biosensing platforms, and delivery vehicles is also discussed.

Indexed as

CellsDNAMacromolecular SubstancesNanoparticlesProteinsSurface PropertiesDNAMacromolecular SubstancesProteins

Identifiers

PMID21671432
PMCPMC3516997
OpenAlexW2091124269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.