ArticleAnais da Academia Brasileira de Ciencias2011
Schistosome serine protease inhibitors: parasite defense or homeostasis?
Article in Anais da Academia Brasileira de Ciencias, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Review
- Article
- Article
- Genetic Diversity of Serine Protease Inhibitors in Myxozoan (Cnidaria, Myxozoa) Fish Parasites.Microorganisms · 2020Article
- The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata.PLoS neglected tropical diseases · 2019Article
- Peptides Derived of Kunitz-Type Serine Protease Inhibitor as Potential Vaccine Against Experimental Schistosomiasis.Frontiers in immunology · 2019Article
- Serpin functions in host-pathogen interactions.PeerJ · 2018Article
- Molecular characterization of serine protease inhibitor isoform 3, SmSPI, from Schistosoma mansoni.Parasitology research · 2016Article
- Functional expression of a novel Kunitz type protease inhibitor from the human blood fluke Schistosoma mansoni.Parasites & vectors · 2015Article
- Species-Specific Serological Detection for Schistosomiasis by Serine Protease Inhibitor (SERPIN) in Multiplex Assay.PLoS neglected tropical diseases · 2015Article
- Comparison of two serpins of Clonorchis sinensis by bioinformatics, expression, and localization in metacercaria.Pathogens and global health · 2014Article
- Natural products as a source for treating neglected parasitic diseases.International journal of molecular sciences · 2013Article
- Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.Acta crystallographica. Section D, Biological crystallography · 2012Article
- A blood fluke serine protease inhibitor regulates an endogenous larval elastase.The Journal of biological chemistry · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Serpins are a structurally conserved family of macromolecular inhibitors found in numerous biological systems. The completion and annotation of the genomes of Schistosoma mansoni and Schistosoma japonicum has enabled the identification by phylogenetic analysis of two major serpin clades. S. mansoni shows a greater multiplicity of serpin genes, perhaps reflecting adaptation to infection of a human host. Putative targets of schistosome serpins can be predicted from the sequence of the reactive center loop (RCL). Schistosome serpins may play important roles in both post-translational regulation of schistosome-derived proteases, as well as parasite defense mechanisms against the action of host proteases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.