Evidence map›Paper›PMID 21670187›Full record

ArticleAntimicrobial agents and chemotherapy2011

In vitro echinocandin susceptibility of Aspergillus isolates from patients enrolled in the Transplant-Associated Infection Surveillance Network.

Shawn R Lockhart, Alicia J Zimbeck, John W Baddley, Kieren A Marr, David R Andes, Thomas J Walsh, Carol A Kauffman, Dimitrios P Kontoyiannis, James I Ito, Peter G Pappas and 1 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Echinocandins - structure, mechanism of action and use in antifungal therapy.Journal of enzyme inhibition and medicinal chemistry · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Susceptibility Testing of Fungi to Antifungal Drugs.Journal of fungi (Basel, Switzerland) · 2018
    Review
  11. Article
  12. Article
  13. Genetic Diversity andAntimicrobial agents and chemotherapy · 2017
    Article
  14. Article
  15. Article
  16. Treatment options in Invasive Aspergillosis.Current treatment options in infectious diseases · 2014
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Shawn R LockhartMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. gyi2@cdc.gov
Alicia J Zimbeck
John W Baddley
Kieren A Marr
David R Andes
Thomas J Walsh
Carol A Kauffman
Dimitrios P Kontoyiannis
James I Ito
Peter G Pappas
Tom Chiller
Centers for Disease Control and Prevention · USBirmingham VA Medical Center · USCancer Research Center · USCity Of Hope National Medical Center · USCornell University · USJohns Hopkins Medicine · USUniversity of Alabama at Birmingham · USUniversity of Michigan–Ann Arbor · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We determined the echinocandin minimum effective concentration (MEC) values for caspofungin, micafungin, and anidulafungin against 288 Aspergillus isolates prospectively collected from transplant patients with proven or probable invasive aspergillosis between 2001 and 2006 as part of the Transplant-Associated Infection Surveillance Network (TRANSNET). We demonstrated that the vast majority of Aspergillus isolates had MEC values at or below the epidemiological cutoff values for caspofungin, micafungin, and anidulafungin, including those from patients who had received caspofungin.

Indexed as

TransplantationAnidulafunginAntifungal AgentsAspergillosisAspergillusCaspofunginDrug Resistance, FungalEchinocandinsHumansLipopeptidesMicafunginMicrobial Sensitivity TestsAnidulafunginAntifungal AgentsCaspofunginEchinocandinsLipopeptidesMicafungin

Identifiers

PMID21670187
PMCPMC3147660
OpenAlexW2096722233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.