ReviewCold Spring Harbor perspectives in biology2011
Small noncoding RNAs in the germline.
Review in Cold Spring Harbor perspectives in biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 59 citations in OpenAlex.
- Remodeling of Germ Cell mRNPs for Translational Control.Biology · 2025Review
- Integrating Inflammatory and Epigenetic Signatures in IBD-Associated Colorectal Carcinogenesis: Models, Mechanisms, and Clinical Implications.International journal of molecular sciences · 2025Review
- Small RNAs, spermatogenesis, and male infertility: a decade of retrospect.Reproductive biology and endocrinology : RB&E · 2023Review
- mirnaQC: a webserver for comparative quality control of miRNA-seq data.Nucleic acids research · 2020Article
- Regulation of Germ Cell mRNPs by eIF4E:4EIP Complexes: Multiple Mechanisms, One Goal.Frontiers in cell and developmental biology · 2020Review
- A piRNA utilizes HILI and HIWI2 mediated pathway to down-regulate ferritin heavy chain 1 mRNA in human somatic cells.Nucleic acids research · 2018Article
- microRNAs selectively protect hub cells of the germline stem cell niche from apoptosis.The Journal of cell biology · 2018Article
- Plasma extracellular RNA profiles in healthy and cancer patients.Scientific reports · 2016Article
- Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila.PLoS genetics · 2016Article
- mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice.Biology open · 2015Article
- Primordial Germ Cell Specification and Migration.F1000Research · 2015Review
- The C. elegans SNAPc component SNPC-4 coats piRNA domains and is globally required for piRNA abundance.Developmental cell · 2014Article
- Non-coding RNA regulation of synaptic plasticity and memory: implications for aging.Ageing research reviews · 2014Review
- AGO3 Slicer activity regulates mitochondria-nuage localization of Armitage and piRNA amplification.The Journal of cell biology · 2014Article
- BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis.The Journal of cell biology · 2014Article
- Connecting the dots of RNA-directed DNA methylation in Arabidopsis thaliana.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2014Review
- Regulation of spermatogenesis by small non-coding RNAs: role of the germ granule.Seminars in cell & developmental biology · 2014Review
- Transgenerational epigenetics in the germline cycle of Caenorhabditis elegans.Epigenetics & chromatin · 2014Article
- Homeland security in the C. elegans germ line: insights into the biogenesis and function of piRNAs.Epigenetics · 2014Review
- Untangling the web: the diverse functions of the PIWI/piRNA pathway.Molecular reproduction and development · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small noncoding RNAs have emerged as potent regulators of gene expression, especially in the germline. We review the biogenesis and regulatory function of three major small noncoding RNA pathways in the germline: The small interfering RNA (siRNA) pathway that leads to the degradation of target mRNAs, the microRNA (miRNA) pathway that mostly represses the translation of target mRNAs, and the newly discovered Piwi-interacting RNA (piRNA) pathway that appears to have diverse functions in epigenetic programming, transposon silencing, and the regulation of mRNA translation and stability. The siRNA and miRNA pathways are present in the germline as well as many somatic tissues, whereas the piRNA pathway is predominantly confined to the germline. Investigation of the three small RNA pathways has started to reveal a new dimension of gene regulation with defining roles in germline specification and development.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.