Trial reportEnvironmental health perspectives2011
Intervention to lower household wood smoke exposure in Guatemala reduces ST-segment depression on electrocardiograms.
Trial report in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Pooled it
- Coronary heart disease and household air pollution from use of solid fuel: a systematic review.British medical bulletin · 2016Pooled it
- Improved stove interventions to reduce household air pollution in low and middle income countries: a descriptive systematic review.BMC public health · 2015Pooled it
- Indoor Air Pollution and Impaired Cardiac Autonomic Function in Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2023Trial
- Short-term differences in cardiac function following controlled exposure to cookstove air pollution: The subclinical tests on volunteers exposed to smoke (STOVES) study.Environment international · 2021Trial
- Systemic effects of wood smoke in a short-term experimental exposure study of atopic volunteers.Journal of occupational and environmental medicine · 2014Trial
- Trial
- Exposure to wood smoke increases arterial stiffness and decreases heart rate variability in humans.Particle and fibre toxicology · 2013Trial
- How Do Household Energy Transitions Work?Research report (Health Effects Institute) · 2025Article
- Assessing the association between household air pollution exposure and child heath in Mongolia: a birth-cohort study.Scientific reports · 2025Article
- Effects of a coal to clean heating policy on acute myocardial infarction in Beijing: a difference-in-differences analysis.The Lancet. Planetary health · 2024Article
- Psychosocial Stress Modifies the Acute Cardiac Health Effects of Traffic-Related Air Pollution.Environment & health (Washington, D.C.) · 2024Article
- Unseen crisis: Revealing the hidden health impact of indoor air pollution-A scoping review.Journal of education and health promotion · 2024Article
- The Impact of Fine Particulate Matter 2.5 on the Cardiovascular System: A Review of the Invisible Killer.Nanomaterials (Basel, Switzerland) · 2022Review
- The Effect of Chronic Inhouse Biomass Fuel Smoke Exposure on Coronary Slow Flow Phenomenon in Women Living in the Eastern Region of Turkey.Medeniyet medical journal · 2022Article
- Exposure to household air pollutants and endothelial dysfunction in rural Bangladesh: A cross-sectional study.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Levels and Determinants of Fine Particulate Matter and Carbon Monoxide in Kitchens Using Biomass and Non-Biomass Fuel for Cooking.International journal of environmental research and public health · 2020Article
- Biomass Fuel Use and Cardiac Function in Nepali Women.Global heart · 2020Article
- Coronary heart disease, hypertension and use of biomass fuel among women: comparative cross-sectional study.BMJ open · 2019Article
- Acute Effects on Blood Pressure Following Controlled Exposure to Cookstove Air Pollution in the STOVES Study.Journal of the American Heart Association · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundA large body of evidence suggests that fine particulate matter (PM) air pollution is a cause of cardiovascular disease, but little is known in particular about the cardiovascular effects of indoor air pollution from household use of solid fuels in developing countries. RESPIRE (Randomized Exposure Study of Pollution Indoors and Respiratory Effects) was a randomized trial of a chimney woodstove that reduces wood smoke exposure.
objectivesWe tested the hypotheses that the stove intervention, compared with open fire use, would reduce ST-segment depression and increase heart rate variability (HRV).
methodsWe used two complementary study designs: a) between-groups comparisons based on randomized stove assignment, and b) before-and-after comparisons within control subjects who used open fires during the trial and received chimney stoves after the trial. Electrocardiogram sessions that lasted 20 hr were repeated up to three times among 49 intervention and 70 control women 38-84 years of age, and 55 control subjects were also assessed after receiving stoves. HRV and ST-segment values were assessed for each 30-min period. ST-segment depression was defined as an average value below -1.00 mm. Personal fine PM [aerodynamic diameter ≤ 2.5 μm (PM₂.₅] exposures were measured for 24 hr before each electrocardiogram.
resultsPM₂.₅ exposure means were 266 and 102 μg/m³ during the trial period in the control and intervention groups, respectively. During the trial, the stove intervention was associated with an odds ratio of 0.26 (95% confidence interval, 0.08-0.90) for ST-segment depression. We found similar associations with the before-and-after comparison. The intervention was not significantly associated with HRV.
conclusionsThe stove intervention was associated with reduced occurrence of nonspecific ST-segment depression, suggesting that household wood smoke exposures affect ventricular repolarization and potentially cardiovascular health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.