Evidence map›Paper›PMID 21667064›Full record

ReviewCellular and molecular life sciences : CMLS2011

Immune biology of Ag-specific γδ T cells in infections.

Zheng W Chen

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Immune Dysfunction in Medication-Related Osteonecrosis of the Jaw.International journal of molecular sciences · 2023
    Review
  5. Article
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  7. Review
  8. Review
  9. Immunization of Vγ2Vδ2 T cells programs sustained effector memory responses that control tuberculosis in nonhuman primates.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  10. Adoptive Transfer of Phosphoantigen-Specific γδ T Cell Subset AttenuatesJournal of immunology (Baltimore, Md. : 1950) · 2017
    Article
  11. Article
  12. Article
  13. Review
  14. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Zheng W ChenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612, USA. zchen@uic.edu
Illinois College · US

Funding

MODEL OF AIDS VIRUS-RELATED PULMONARY TUBERCULOSISR01HL064560 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1999 to 2014
$9.5M
SIV/MYCOBACTERIUM COINFECTIONR01RR013601 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1998 to 2008
$4.4M
Ag-specific gamma delta T cells and immunity to TB/AIDS-related TBR01OD015092 · OD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 2013 to 2017
$3.0M
NCRR NIH HHS R01 RR013601NCRR NIH HHS RR13601NHLBI NIH HHS HL64560NHLBI NIH HHS R01 HL064560NIH HHS R01 OD015092
6 · The paper itself

Abstract

Accumulating evidence suggests that human γδ T cells act as non-classical T cells and contribute to both innate and adaptive immune responses in infections. Vγ2 Vδ2 T (also termed Vγ9 Vδ2 T) cells exist only in primates, and in humans represent a dominant circulating γδ T-cell subset. Primate Vγ2 Vδ2 T cells are the only γδ T cell subset capable of recognizing microbial phosphoantigen. Since nonhuman primate Vγ2 Vδ2 T cells resemble their human counterparts, in-depth studies have been undertaken in macaques to understand the biology and function of human Vγ2 Vδ2 T cells. This article reviews the recent progress for immune biology of Vγ2 Vδ2 T cells in infections.

Indexed as

Adaptive ImmunityAnimalsAntigens, BacterialHumansLymphocyte ActivationMacacaMycobacterium tuberculosisReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesTuberculosisAntigens, BacterialReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID21667064
PMCPMC3593731
OpenAlexW1963522518

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.