ArticlePLoS neglected tropical diseases2011
A cross-sectional study of people with epilepsy and neurocysticercosis in Tanzania: clinical characteristics and diagnostic approaches.
Article in PLoS neglected tropical diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Comorbidities of epilepsy in low and middle-income countries: systematic review and meta-analysis.Scientific reports · 2020Pooled it
- The causal relationship between neurocysticercosis infection and the development of epilepsy - a systematic review.Infectious diseases of poverty · 2017Pooled it
- Prevalence of neurocysticercosis and its characteristics among people with epileptic seizures and progressively worsening severe headaches in 60 villages in three provinces of Burkina Faso.PLoS neglected tropical diseases · 2026Trial
- Diagnostic Accuracy of Antigen ELISA and Western Blot IgG for Neurocysticercosis in People Living with HIV/AIDS in Tanzania.Tropical medicine and infectious disease · 2025Article
- Correlation of serum screening and neuroimaging studies: A comparative analysis for diagnostic evaluation of neurocysticercosis among people with epilepsy attending mental health clinics in selected district hospitals of Tanzania.PLoS neglected tropical diseases · 2025Article
- Neurocysticercosis Prevalence and Characteristics in Communities of Sinda District in Zambia: A Cross-Sectional Study.Journal of epidemiology and global health · 2024Article
- Report of three patients with extensive neurocysticercosis in rural southern Tanzania: neurological, serological and neuroradiological findings.Journal of medical case reports · 2023Article
- Nodding syndrome, a case-control study in Mahenge, Tanzania: Onchocerca volvulus and not Mansonella perstans as a risk factor.PLoS neglected tropical diseases · 2023Article
- Quantitative risk assessment for humanVeterinary world · 2023Article
- Characteristics of people with epilepsy and Neurocysticercosis in three eastern African countries-A pooled analysis.PLoS neglected tropical diseases · 2022Article
- Epidemiological, clinical and radiological characteristics of people with neurocysticercosis in Tanzania-A cross-sectional study.PLoS neglected tropical diseases · 2022Article
- Trial Design of a Prospective Multicenter Diagnostic Accuracy Study of a Point-of-Care Test for the Detection ofDiagnostics (Basel, Switzerland) · 2021Article
- High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo.BMC infectious diseases · 2021Article
- Neurocysticercosis in patients with active epilepsy in the tea garden community of Assam, Northeast India.Scientific reports · 2021Article
- Evidence for Transmission ofFrontiers in veterinary science · 2021Article
- Porcine cysticercosis in slaughtered pigs and factors related toThe Pan African medical journal · 2019Article
- Article
- Mortality of neurological disorders in Tanzania: analysis of baseline data from sample vital registration with verbal autopsy (SAVVY).Global health action · 2019Article
- Extraparenchymal neurocysticercosis: Demographic, clinicoradiological, and inflammatory features.PLoS neglected tropical diseases · 2017Article
- Cysticercosis and epilepsy in rural Tanzania: a community-based case-control and imaging study.Tropical medicine & international health : TM & IH · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurocysticercosis (NCC) is a major cause of epilepsy in regions where pigs are free-ranging and hygiene is poor. Pork production is expected to increase in the next decade in sub-Saharan Africa, hence NCC will likely become more prevalent. In this study, people with epilepsy (PWE, n=212) were followed up 28.6 months after diagnosis of epilepsy. CT scans were performed, and serum and cerebrospinal fluid (CSF) of selected PWE were analysed. We compared the demographic data, clinical characteristics, and associated risk factors of PWE with and without NCC. PWE with NCC (n=35) were more likely to be older at first seizure (24.3 vs. 16.3 years, p=0.097), consumed more pork (97.1% vs. 73.6%, p=0.001), and were more often a member of the Iraqw tribe (94.3% vs. 67.8%, p=0.005) than PWE without NCC (n=177). PWE and NCC who were compliant with anti-epileptic medications had a significantly higher reduction of seizures (98.6% vs. 89.2%, p=0.046). Other characteristics such as gender, seizure frequency, compliance, past medical history, close contact with pigs, use of latrines and family history of seizures did not differ significantly between the two groups. The number of NCC lesions and active NCC lesions were significantly associated with a positive antibody result. The electroimmunotransfer blot, developed by the Centers for Disease Control and Prevention, was more sensitive than a commercial western blot, especially in PWE and cerebral calcifications. This is the first study to systematically compare the clinical characteristics of PWE due to NCC or other causes and to explore the utility of two different antibody tests for diagnosis of NCC in sub-Saharan Africa.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.