ArticleIn vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association2011
Trichomes + roots + ROS = artemisinin: regulating artemisinin biosynthesis in Artemisia annua L.
Article in In vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 72 citations in OpenAlex.
- Comparison of phytochemical properties and expressional profiling of artemisinin synthesis-related genes in variousHeliyon · 2024Article
- Enhancing activity of β-lactam and fluoroquinolones antibiotics by artemisinin and its derivatives against MDRFrontiers in veterinary science · 2022Article
- Glandular trichomes: new focus on horticultural crops.Horticulture research · 2021Review
- Recent Advances in the Synthetic Biology of Natural Drugs.Frontiers in bioengineering and biotechnology · 2021Review
- Identification of the Volatile Compounds and Observation of the Glandular Trichomes inPlants (Basel, Switzerland) · 2020Article
- Oligomers of carrageenan regulate functional activities and artemisinin production in Artemisia annua L. exposed to arsenic stress.Protoplasma · 2020Article
- Transcriptome analyses revealed the ultraviolet B irradiation and phytohormone gibberellins coordinately promoted the accumulation of artemisinin inChinese medicine · 2020Article
- Artemisia annua L. and photoresponse: from artemisinin accumulation, volatile profile and anatomical modifications to gene expression.Plant cell reports · 2020Article
- Red and Blue Light Promote the Accumulation of Artemisinin in Artemisia Annua L.Molecules (Basel, Switzerland) · 2018Article
- Biotechnological approaches for artemisinin production in Artemisia.World journal of microbiology & biotechnology · 2018Review
- Root regulation of artemisinin production in Artemisia annua: trichome and metabolite evidence.Planta · 2016Article
- Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites.Journal of natural medicines · 2016Review
- Artemisinin production by plant hairy root cultures in gas- and liquid-phase bioreactors.Plant cell reports · 2016Article
- Two conserved oligosaccharyltransferase catalytic subunits required for N-glycosylation exist in Spartina alterniflora.Botanical studies · 2015Article
- Transgenic approach to increase artemisinin content in Artemisia annua L.Plant cell reports · 2014Review
- Antimicrobial activity of artemisinin and precursor derived from in vitro plantlets of Artemisia annua L.BioMed research international · 2014Article
- 21st century natural product research and drug development and traditional medicines.Natural product reports · 2013Review
- Artemisinin production and precursor ratio in full grown Artemisia annua L. plants subjected to external stress.Planta · 2013Article
- The effect of roots and media constituents on trichomes and artemisinin production in Artemisia annua L.Plant cell reports · 2013Article
- Effect of external stress on density and size of glandular trichomes in full-grown Artemisia annua, the source of anti-malarial artemisinin.AoB PLANTS · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Artemisinin is a highly effective sesquiterpene lactone therapeutic produced in the plant, Artemisia annua. Despite its efficacy against malaria and many other infectious diseases and neoplasms, the drug is in short supply mainly because the plant produces low levels of the compound. This review updates the current understanding of artemisinin biosynthesis with a special focus on the emerging knowledge of how biosynthesis of the compound is regulated in planta.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.