Evidence map›Paper›PMID 21666754›Full record

ArticleViruses2011

Un-“ESCRT”-ed budding.

Mark Yondola, Carol Carter

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Mark YondolaDepartment of Microbiology, Mount Sinai School of Medicine, New York, NY 10128, USA. mark.yondola@mssm.edu
Carol Carter
Icahn School of Medicine at Mount Sinai · USStony Brook University · US

Funding

Cellular Proteins Involved in Trafficking of HIV-1R01AI068463 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI CARTER, CAROL A · 2007 to 2010
$1.4M
NIAID NIH HHS R01 AI068463
6 · The paper itself

Abstract

In their recent publication, Rossman et al. describe how the inherent budding capability of its M2 protein allows influenza A virus to bypass recruitment of the cellular ESCRT machinery enlisted by several other enveloped RNA and DNA viruses, including HIV, Ebola, rabies, herpes simplex type 1 and hepatitis B. Studies from the same laboratory and other laboratories indicate that budding of plasmid-derived virus-like particles can be mediated by the influenza virus hemagglutinin and neuraminidase proteins in the absence of M2. These events are also independent of canonical ESCRT components. Understanding how intrinsic properties of these influenza virus proteins permit ESCRT-independent budding expands our understanding of the budding process itself.

Indexed as

Cell MembraneEndosomal Sorting Complexes Required for TransportHemagglutininsInfluenza A virusNeuraminidaseViral Matrix ProteinsViroporin ProteinsVirus ReleaseEndosomal Sorting Complexes Required for TransportHemagglutininsM2 protein, Influenza A virusNeuraminidaseViral Matrix ProteinsViroporin ProteinsbuddingcholesterolESCRTHAinfluenza virusM2membrane raftsNA

Identifiers

PMID21666754
PMCPMC3110670
OpenAlexW2029218410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.