Trial reportEnvironmental health perspectives2011
In-traffic air pollution exposure and CC16, blood coagulation, and inflammation markers in healthy adults.
Trial report in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- The short- and long-term associations of particulate matter with inflammation and blood coagulation markers: A meta-analysis.Environmental pollution (Barking, Essex : 1987) · 2020Pooled it
- Particulate matter exposure and health impacts of urban cyclists: a randomized crossover study.Environmental health : a global access science source · 2018Trial
- Composition of PM affects acute vascular inflammatory and coagulative markers - the RAPTES project.PloS one · 2013Trial
- The Association Between Air Pollution Exposure and White Blood Cell Counts: A Nationwide Cross-Sectional Survey in South Korea.Journal of clinical medicine · 2024Article
- Short-term exposure to air pollution on peripheral white blood cells and inflammation biomarkers: a cross-sectional study on rural residents.BMC public health · 2024Article
- Association between short-term exposure to ambient air pollutants and biomarkers indicative of inflammation and oxidative stress: a cross-sectional study using KoGES-HEXA data.Environmental health and preventive medicine · 2024Article
- Associations between Short-Term Air Pollution Exposure and the Peripheral Leukocyte Distribution in the Adult Male Population in Beijing, China.International journal of environmental research and public health · 2023Article
- Association between air pollution and CSF sTREM2 in cognitively normal older adults: The CABLE study.Annals of clinical and translational neurology · 2022Article
- Metabolomic signatures of the short-term exposure to air pollution and temperature.Environmental research · 2021Article
- Estimation of the Inhaled Dose of Pollutants in Different Micro-Environments: A Systematic Review of the Literature.Toxics · 2021Review
- Ambient PMEnvironment international · 2021Article
- The Association of White Blood Cells and Air Pollutants-A Population-Based Study.International journal of environmental research and public health · 2021Observational
- Application of high-resolution metabolomics to identify biological pathways perturbed by traffic-related air pollution.Environmental research · 2021Article
- Long-term exposure to outdoor air pollution and risk factors for cardiovascular disease within a cohort of older men in Perth.PloS one · 2021Article
- Pesticide risk perceptions among bystanders of aerial spraying on bananas in Costa Rica.Environmental research · 2020Article
- Impacts of air pollution, temperature, and relative humidity on leukocyte distribution: An epigenetic perspective.Environment international · 2019Article
- Air Pollution and Other Environmental Modulators of Cardiac Function.Comprehensive Physiology · 2017Review
- Oxidative Stress and Cardiovascular Risk: Obesity, Diabetes, Smoking, and Pollution: Part 3 of a 3-Part Series.Journal of the American College of Cardiology · 2017Review
- Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children.Environmental health perspectives · 2017Article
- Scenario-based analysis of traffic-related PMEnvironmental science and pollution research international · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure to traffic-related air pollution is a risk factor for cardiovascular events, probably involving mechanisms of inflammation and coagulation. Little is known about effects of the short exposures encountered while participating in traffic.
objectivesThe objective of the study was to examine effects of exposure of commuters to air pollution on cardiovascular biomarkers.
methodsThirty-four healthy adult volunteers commuted for 2 hr by bus, car, or bicycle during the morning rush hour. During the commute, exposure to particle number, particulate matter (PM) ≤ 2.5 µm in aerodynamic diameter (PM2.5), PM ≤ 10 µm in diameter (PM10), and soot was measured. We estimated inhaled doses based on heart rate monitoring. Shortly before exposure and 6 hr after exposure, blood samples were taken and analyzed for CC16 (Clara cell protein 16), blood cell count, coagulation markers, and inflammation markers. Between June 2007 and June 2008, 352 pre- and postexposure blood samples were collected on 47 test days. We used mixed models to analyze the associations between exposure and changes in health parameters.
resultsWe observed no consistent associations between the air pollution exposures and doses and the various biomarkers that we investigated.
conclusionsAir pollution exposure during commuting was not consistently associated with acute changes in inflammation markers, blood cell counts, or blood coagulation markers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.