Evidence map›Paper›PMID 21665298›Full record

ReviewTrends in neurosciences2011

Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators.

Jennifer A Mohawk, Joseph S Takahashi

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  13. Circadian influences on sudden cardiac death and cardiac electrophysiology.Journal of molecular and cellular cardiology · 2025
    Review
  14. Article
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  18. Feeding behavior modifies the circadian variation in RR and QT intervals by distinct mechanisms in mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
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  20. Review

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer A MohawkDepartment of Neuroscience and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.
Joseph S Takahashi

Funding

Chemical and Genetic Manipulation of Circadian SystemsP50MH074924 · NIMH · NORTHWESTERN UNIVERSITY · PI TAKAHASHI, JOSEPH S · 2005 to 2009
$10.4M
Identifying circadian rhythm genes from mouse mutantsR01MH078024 · NIMH · NORTHWESTERN UNIVERSITY · PI TAKAHASHI, JOSEPH S · 2007 to 2011
$1.8M
Howard Hughes Medical InstituteNIMH NIH HHS P50 MH074924NIMH NIH HHS R01 MH078024
6 · The paper itself

Abstract

The suprachiasmatic nucleus (SCN) of the hypothalamus is the site of the master circadian pacemaker in mammals. The individual cells of the SCN are capable of functioning independently from one another and therefore must form a cohesive circadian network through intercellular coupling. The network properties of the SCN lead to coordination of circadian rhythms among its neurons and neuronal subpopulations. There is increasing evidence for multiple interconnected oscillators within the SCN, and in this review we will highlight recent advances in our knowledge of the complex organization and function of the cellular and network-level SCN clock. Understanding the way in which synchrony is achieved between cells in the SCN will provide insight into the means by which this important nucleus orchestrates circadian rhythms throughout the organism.

Indexed as

Models, NeurologicalAnimalsCircadian ClocksCircadian RhythmHumansNerve NetNeuronsSuprachiasmatic Nucleus

Identifiers

PMID21665298
PMCPMC3775330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.