ArticleBMC infectious diseases2011
A molecular epidemiological study of respiratory viruses detected in Japanese children with acute wheezing illness.
Article in BMC infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of respiratory viruses using polymerase chain reaction in children with wheezing, a systematic review and meta-analysis.PloS one · 2020Pooled it
- The prevalence and role of human respiratory syncytial virus in pediatric respiratory tract infections: a systematic review and meta-analysis of global data.EClinicalMedicine · 2026Article
- Molecular characterization of human rhinovirus strains detected in pediatric acute respiratory tract infections.Iranian journal of microbiology · 2026Article
- Molecular detection and genotyping of HMPV in patients with severe acute respiratory infection in India.Annals of medicine · 2024Article
- Co-infections of SARS-CoV-2 with respiratory syncytial virus and human influenza A in patients with symptoms of COVID-19 in Ghana: A retrospective study.New microbes and new infections · 2024Article
- The role of gut microbiome in the complex relationship between respiratory tract infection and asthma.Frontiers in microbiology · 2023Review
- Risk Factors Affecting Development and Persistence of Preschool Wheezing: Consensus Document of the Emilia-Romagna Asthma (ERA) Study Group.Journal of clinical medicine · 2022Article
- Genetic characterization of highly pathogenic avian influenza A (H5N8) virus isolated from domestic geese in Iraq, 2018.BMC veterinary research · 2021Article
- Integrated Microfluidic Preconcentration and Nucleic Amplification System for Detection of Influenza A Virus H1N1 in Saliva.Micromachines · 2020Article
- Respiratory Viruses and Atypical Bacteria Co-Infection in Children with Acute Respiratory Infection.Open access Macedonian journal of medical sciences · 2018Article
- Asthma exacerbations in a subtropical area and the role of respiratory viruses: a cross-sectional study.BMC pulmonary medicine · 2018Article
- Clinical and laboratory profiles of hospitalized children with acute respiratory virus infection.Korean journal of pediatrics · 2018Article
- Prevalence of Human rhinovirus infection in young children with acute wheezing.The Gazette of the Egyptian Paediatric Association · 2018Article
- BA9 lineage of respiratory syncytial virus from across the globe and its evolutionary dynamics.PloS one · 2018Article
- The molecular epidemiology of respiratory viruses associated with asthma attacks: A single-center observational study in Japan.Medicine · 2017Observational
- Increased Systemic Cytokine/Chemokine Expression in Asthmatic and Non-asthmatic Patients with Bacterial, Viral or Mixed Lung Infection.Scandinavian journal of immunology · 2017Article
- Evaluation of the Luminex xTAG Respiratory Viral Panel FAST v2 assay for detection of multiple respiratory viral pathogens in nasal and throat swabs in Vietnam.Wellcome open research · 2017Article
- Viruses causing severe acute respiratory infections (SARI) in children ≤5 years of age at a tertiary care hospital in Rajasthan, India.The Indian journal of medical research · 2016Article
- Are respiratory viruses involved in preseasonal symptoms or severity in Japanese cedar pollinosis?Allergy & rhinology (Providence, R.I.) · 2016Article
- Clinical risk factors associated with the development of wheezing in children less than 2 years of age who required hospitalization for viral lower respiratory tract infections.Korean journal of pediatrics · 2015Article
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Authors and funding
16 authors.
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Abstract
backgroundRecent studies strongly suggest that some respiratory viruses are associated with the induction of acute wheezing and/or exacerbation of bronchial asthma. However, molecular epidemiology of these viruses is not exactly known.
methodsUsing PCR technology, we attempted to detect various respiratory viruses from 115 Japanese children. Furthermore, the detected viruses were subjected to homology, pairwise distance, and phylogenetic analysis.
resultsViruses were detected from 99 (86.1%) patients. Respiratory syncytial virus (RSV) alone and human rhinovirus (HRV) alone were detected in 47 (40.9%) and 36 (31.3%) patients, respectively. Both RSV and HRV were detected in 14 (12.2%) patients. Human metapneumovirus (HMPV) alone and human parainfluenza virus (HPIV) alone were detected in 1 (0.9%) patient each, respectively. Homology and phylogenetic analyses showed that the RSV and HRV strains were classified into genetically diverse species or subgroups. In addition, RSV was the dominant virus detected in patients with no history of wheezing, whereas HRV was dominant in patients with a history of wheezing.
conclusionsThe results suggested that these genetically diverse respiratory viruses, especially RSV and HRV, might be associated with wheezing in Japanese children.
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