ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2012
Enterococcus faecalis from patients with chronic periodontitis: virulence and antimicrobial resistance traits and determinants.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebo- controlled trial with 9-month follow-up.Journal of applied oral science : revista FOB · 2018Trial
- Peridontopathogenic key species in correlation to the current classification system.Clinical oral investigations · 2025Article
- Phenotypic and genotypic characterization of Enterococcus faecalis and Enterococcus faecium isolated from fish, vegetables, and humans.Scientific reports · 2024Article
- Phytochemical profile and antimicrobial activity of essential oils from two Syzygium species against selected oral pathogens.BMC complementary medicine and therapies · 2023Article
- The Antimicrobial and Anti-Biofilm Effects ofClinics and practice · 2022Article
- Antimicrobial Resistance, Biofilm Formation, and Virulence Genes inAntibiotics (Basel, Switzerland) · 2022Article
- CRISPR-Virulence · 2020Article
- The effect of smear layer removal on E. faecalis leakage and bond strength of four resin-based root canal sealers.BMC oral health · 2018Article
- Virulence Genes, Antibiotic Resistance and Capsule Locus Polymorphisms inInfection & chemotherapy · 2018Article
- Prevalence and phenotypic characterization of Enterococcus species isolated from clinical samples of pediatric patients in Jimma University Specialized Hospital, south west Ethiopia.BMC research notes · 2018Article
- Enterococcus Species in the Oral Cavity: Prevalence, Virulence Factors and Antimicrobial Susceptibility.PloS one · 2016Article
- Characterization of Enterococcus faecalis isolates originating from different sources for their virulence factors and genes, antibiotic resistance patterns, genotypes and biofilm production.Iranian journal of veterinary research · 2015Article
- Expression of Alzheimer-Type Neurofibrillary Epitopes in Primary Rat Cortical Neurons Following Infection with Enterococcus faecalis.Frontiers in aging neuroscience · 2015Article
- Enterococcus faecalis from Food, Clinical Specimens, and Oral Sites: Prevalence of Virulence Factors in Association with Biofilm Formation.Frontiers in microbiology · 2015Article
- Perturbation of the indigenous rat oral microbiome by ciprofloxacin dosing.Molecular oral microbiology · 2013Article
- Developing insights into the mechanisms of evolution of bacterial pathogens from whole-genome sequences.Future microbiology · 2012Review
- Enterococci in the oral cavity of periodontitis patients from different urban socioeconomic groups.Dental research journalArticle
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the presence of virulence and resistance traits, as well as their genetic determinants in subgingival Enterococcus faecalis from patients with chronic periodontitis. Twenty-four E. faecalis strains from a previously multi-locus sequence typing (MLST)-characterized strain collection were examined for virulence-associated phenotypes, antimicrobial susceptibility, and virulence- and antimicrobial-resistant determinants. Gelatinase, hemolysin, and biofilm production were detected in 50, 17, and 100% of the strains, respectively. Genes encoding adherence factors such as ace, efaA, and bopD were detected in all isolates. Other putative virulence determinants, i.e., EF3314, gelE, asa, esp, cylA, ef1841/fsrC, and asa373, were found in a portion of the strains. Different levels of resistance were observed in these strains, with two strains expressing high-level resistance to erythromycin and gentamicin. The integrase gene and accessory gene(s) of the Tn916/Tn1545 family were detected in ten strains. A direct link was shown between the presence of Tn916/Tn1545-like elements and resistance to doxycycline and/or erythromycin. The results demonstrated that virulence and antibiotic resistance determinants were prevalent in oral E. faecalis strains. It implicates that oral E. faecalis might play a role in the pathogenesis of chronic periodontitis and be a potential reservoir for the transferable elements of virulence and antimicrobial resistance.
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