ArticlePathology research international2011
Osteoimmunopathology in HIV/AIDS: A Translational Evidence-Based Perspective.
Article in Pathology research international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Effects of vitamin D supplementation on the bone specific biomarkers in HIV infected individuals under treatment with efavirenz.BMC research notes · 2012Trial
- Article
- Translational research of temporomandibular joint pathology: a preliminary biomarker and fMRI study.Journal of translational medicine · 2020Article
- Inflammation status in HIV-positive individuals correlates with changes in bone tissue quality after initiation of ART.The Journal of antimicrobial chemotherapy · 2019Article
- Osteonecrosis of the femoral head in people living with HIV: anatomopathological description and p24 antigen test.HIV/AIDS (Auckland, N.Z.) · 2018Article
- Comorbidities associated with HIV and antiretroviral therapy (clinical sciences): a workshop report.Oral diseases · 2016Article
- The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation.Aging cell · 2015Article
- Stakeholder engagement analysis - a bioethics dilemma in patient-targeted intervention: patients with temporomandibular joint disorders.Journal of translational medicine · 2015Review
- Network-based analysis of comorbidities risk during an infection: SARS and HIV case studies.BMC bioinformatics · 2014Article
- Type 1 interferons suppress accelerated osteoclastogenesis and prevent loss of bone mass during systemic inflammatory responses to Pneumocystis lung infection.The American journal of pathology · 2012Article
- Reliability of Quality Assessments in Research Synthesis: Securing the Highest Quality Bioinformation for HIT.Bioinformation · 2012Article
- Temporomandibular disorders in patients with HIV: a cross-sectional study.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infection with the human immunodeficiency virus-1 (HIV) and the resulting acquired immune deficiency syndrome (AIDS) alter not only cellular immune regulation but also the bone metabolism. Since cellular immunity and bone metabolism are intimately intertwined in the osteoimmune network, it is to be expected that bone metabolism is also affected in patients with HIV/AIDS. The concerted evidence points convincingly toward impaired activity of osteoblasts and increased activity of osteoclasts in patients with HIV/AIDS, leading to a significant increase in the prevalence of osteoporosis. Research attributes these outcomes in part at least to the ART, PI, and HAART therapies endured by these patients. We review and discuss these lines of evidence from the perspective of translational clinically relevant complex systematic reviews for comparative effectiveness analysis and evidence-based intervention on a global scale.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.