ArticleEvidence-based complementary and alternative medicine : eCAM2011
Action of Coriandrum sativum L. Essential Oil upon Oral Candida albicans Biofilm Formation.
Article in Evidence-based complementary and alternative medicine : eCAM, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Salivary microbiome responses to chlorhexidine and Coriandrum sativum essential oil mouthwashes in patients with periodontitis in a randomized 2-week clinical trial.Clinical oral investigations · 2026Trial
- Impact of Plant Part and Age ofMolecules (Basel, Switzerland) · 2026Article
- Physical Properties of New Silica-Based Denture Surface Coating.Nanomaterials (Basel, Switzerland) · 2025Article
- Biofilm-Associated Candidiasis: Pathogenesis, Prevalence, Challenges and Therapeutic Options.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Essential Oils as Alternative Green Broad-Spectrum Biocides.Plants (Basel, Switzerland) · 2024Review
- Potential Antimicrobial and Cytotoxic Activity ofAntibiotics (Basel, Switzerland) · 2024Article
- Unveiling the mechanism of essential oil action against skin pathogens: from ancient wisdom to modern science.Archives of microbiology · 2024Review
- Anticandida and antibiofilm activities of extract from Schinopsis brasiliensis Engl. against Candida spp.Brazilian oral research · 2024Article
- Chemical Variability of the Essential Oils from Two Portuguese Apiaceae:Plants (Basel, Switzerland) · 2023Article
- Decoding the host-pathogen interspecies molecular crosstalk during oral candidiasis in humans: anFrontiers in genetics · 2023Article
- Oral Cavity andPathogens (Basel, Switzerland) · 2022Review
- The Current Antimicrobial and Antibiofilm Activities of Synthetic/Herbal/Biomaterials in Dental Application.BioMed research international · 2022Review
- Natural Compounds for Preventing Ear, Nose, and Throat-Related Oral Infections.Plants (Basel, Switzerland) · 2021Review
- Biomaterials for the Prevention of Oral Candidiasis Development.Pharmaceutics · 2021Review
- The Use of Essential Oils and Their Isolated Compounds for the Treatment of Oral Candidiasis: A Literature Review.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Synthesis, Antifungal Activity, and Cytotoxicity of AgBr-NP@CTMAB Hybrid and Its Application in PMMA.International journal of nanomedicine · 2021Article
- Essential Oils as Potential Alternative Biocontrol Products against Plant Pathogens and Weeds: A Review.Foods (Basel, Switzerland) · 2020Review
- Antibacterial Activities of Herbal Toothpastes Combined with Essential Oils againstPathogens (Basel, Switzerland) · 2019Article
- Fusion of a chitin-binding domain to an antibacterial peptide to enhance resistance to3 Biotech · 2018Article
- Essential Oils and Antifungal Activity.Pharmaceuticals (Basel, Switzerland) · 2017Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The efficacy of extracts and essential oils from Allium tuberosum, Coriandrum sativum, Cymbopogon martini, Cymbopogon winterianus, and Santolina chamaecyparissus was evaluated against Candida spp. isolates from the oral cavity of patients with periodontal disease. The most active oil was fractionated and tested against C. albicans biofilm formation. The oils were obtained by water-distillation and the extracts were prepared with macerated dried plant material. The Minimal Inhibitory Concentration-MIC was determined by the microdilution method. Chemical characterization of oil constituents was performed using Gas Chromatography and Mass Spectrometry (GC-MS). C. sativum activity oil upon cell and biofilm morphology was evaluated by Scanning Electron Microscopy (SEM). The best activities against planktonic Candida spp. were observed for the essential oil and the grouped F(8-10) fractions from C. sativum. The crude oil also affected the biofilm formation in C. albicans causing a decrease in the biofilm growth. Chemical analysis of the F(8-10) fractions detected as major active compounds, 2-hexen-1-ol, 3-hexen-1-ol and cyclodecane. Standards of these compounds tested grouped provided a stronger activity than the oil suggesting a synergistic action from the major oil constituents. The activity of C. sativum oil demonstrates its potential for a new natural antifungal formulation.
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Registered trials
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