ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2011
LSPR Biosensor Signal Enhancement Using Nanoparticle-Antibody Conjugates.
Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 235 citations in OpenAlex.
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- Localized surface plasmon resonance sensing of Trenbolone acetate dopant using silver nanoparticles.Scientific reports · 2024Article
- Calligraphy of Nanoplasmonic Bioink-Based Multiplex Immunosensor for Precision Immune Monitoring and Modulation.ACS applied materials & interfaces · 2023Article
- Recent advances in the detection of glioblastoma, from imaging-based methods to proteomics and biosensors: A narrative review.Cancer cell international · 2023Review
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- Anisotropic CdSe Tetrapods in Vortex Flow for Removing Non-Specific Binding and Increasing Protein Capture.Sensors (Basel, Switzerland) · 2022Article
- Designing Functional Bionanoconstructs for EffectiveBioconjugate chemistry · 2022Review
- Fabrication of Fragment Antibody-Enzyme Complex as a Sensing Element for Immunosensing.International journal of molecular sciences · 2022Review
- Plasmonic nano-antimicrobials: properties, mechanisms and applications in microbe inactivation and sensing.Nanoscale · 2021Review
- Review
- Exploring the synergy of radiative coupling and substrate undercut in arrayed gold nanodisks for economical, ultra-sensitive label-free biosensing.IEEE sensors journal · 2021Article
- Nanomaterials to tackle the COVID-19 pandemic.Emergent materials · 2021Review
- Nanostructured Color Filters: A Review of Recent Developments.Nanomaterials (Basel, Switzerland) · 2020Review
- Gold Nanoparticle-Enhanced and Roll-to-Roll Nanoimprinted LSPR Platform for Detecting Interleukin-10.Frontiers in chemistry · 2020Article
- Review
- Microscale and Nanoscale Electrophotonic Diagnostic Devices.Cold Spring Harbor perspectives in medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A method to amplify the wavelength shift observed from localized surface plasmon resonance (LSPR) bioassays is developed using gold nanoparticle-labeled antibodies. The technique, which involves detecting surface-bound analytes using gold nanoparticle conjugated antibodies, provides a way to enhance LSPR shifts for more sensitive detection of low-concentration analytes. Using the biotin and antibiotin binding pair as a model, we demonstrate up to a 400% amplification of the shift upon antibody binding to analyte. In addition, the antibody-nanoparticle conjugate improves the observed binding constant by 2 orders of magnitude, and the limit of detection by nearly 3 orders of magnitude. This amplification strategy provides a way to improve the sensitivity of plasmon-based bioassays, paving the way for single molecule-based detection and clinically relevant diagnostics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.