ArticleJournal of biomedicine & biotechnology2011
Induction and flow cytometry identification of tetraploids from seed-derived explants through colchicine treatments in Catharanthus roseus (L.) G. Don.
Article in Journal of biomedicine & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 80 citations in OpenAlex.
- Mutagenic and physiological impacts of colchicine on growth, flowering behavior, and ISSR-based genetic variability in Calendula officinalis L.BMC plant biology · 2026Article
- Telomere-to-telomere genome assembly and multiomics analyses illustrate the high accumulation of quercetin glucosides in tetraploidHorticulture research · 2026Article
- Phenotypic and Metabolic Variations Induced by Autopolyploidization in Chinese Jujube Cultivars.Plants (Basel, Switzerland) · 2025Article
- Genomic and evolutionary evidence for drought adaptation of allopolyploid Brachypodium hybridum.Journal of experimental botany · 2025Article
- In vitro synthetic polyploidization and enhancement of anticancer compounds in Catharanthus Roseus (L.) G. Don important cultivars.Scientific reports · 2025Article
- Oryzalin-induced polyploidy inFrontiers in plant science · 2025Article
- Molecular validation of genetically transformedHeliyon · 2024Article
- Transcriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor.BMC plant biology · 2023Article
- In Vitro Induction of Interspecific Hybrid and Polyploidy Derived fromPlants (Basel, Switzerland) · 2023Article
- The Light- and Jasmonic Acid-InducedInternational journal of molecular sciences · 2023Article
- Retention of Mutations in Colchicine-Induced Ornamental SucculentPlants (Basel, Switzerland) · 2022Article
- Salinity Tolerance in a Synthetic Allotetraploid Wheat (SFrontiers in plant science · 2022Article
- Phenotypic diploidization in plant functional traits uncovered by synthetic neopolyploids in Dianthus broteri.Journal of experimental botany · 2021Article
- Induced autopolyploidy-a promising approach for enhanced biosynthesis of plant secondary metabolites: an insight.Journal, genetic engineering & biotechnology · 2021Review
- Integration of metabolome and transcriptome reveals flavonoid accumulation in the intergeneric hybrid between Brassica rapa and Raphanus sativus.Scientific reports · 2019Article
- Induction, identification and genetics analysis of tetraploidRoyal Society open science · 2019Article
- Molecular basis underlying the successful invasion of hexaploid cytotypes ofEcology and evolution · 2019Article
- Ornamental exterior versus therapeutic interior of Madagascar periwinkle (Catharanthus roseus): the two faces of a versatile herb.TheScientificWorldJournal · 2015Review
- Overproduction of valuable methoxylated flavones in induced tetraploid plants of Dracocephalum kotschyi Boiss.Botanical studies · 2014Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tetraploid plants of Catharanthus roseus (L.) G. Don was obtained by colchicine induction from seeds explants, and the ploidy of the plants was identified by flow cytometry. The optimal treatment is 0.2% colchicine solution treated for 24 hours, and the induction rate reaches up to 30%. Comparing with morphological characteristics and growth habits between tetraploids and the control, we found that tetraploids of C. roseus had larger stoma and more branches and leaves. HPLC analysis showed tetraploidization could increase the contents of terpenoid indole alkaloids in C. roseus. Thus, tetraploidization could be used to produce higher alkaloids lines for commercial use. QRT-PCR results showed that the expression of enzymes involved in terpenoid indole alkaloids biosynthesis pathway had increased in the tetraploid plants. To our knowledge, this was the first paper to explore the secondary metabolism in autotetraploid C. roseus induced by colchicine.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.