Evidence map›Paper›PMID 21659854›Full record

ReviewCurrent opinion in allergy and clinical immunology2011

Biologic modulators in allergic and autoinflammatory diseases.

Lori Broderick, Louanne M Tourangeau, Arthur Kavanaugh, Stephen I Wasserman

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in allergy and clinical immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lori BroderickDivision of Rheumatology, Allergy and Immunology, Department of Medicine, University of California San Diego, San Diego, California 92093, USA. lbroderick@ucsd.edu
Louanne M Tourangeau
Arthur Kavanaugh
Stephen I Wasserman
University of California, San Diego · US

Funding

TRAINING IN MOLECULAR &CELL BIOLOGY OF ALLERGYT32AI007469 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 1994 to 2024
$6.9M
NIAID NIH HHS T32 AI007469PHS HHS T32 A107469
6 · The paper itself

Abstract

purpose of reviewThe advent of molecular techniques has resulted in the ability to tailor medications to specific protein targets. This review will emphasize several biological therapies, specifically directed toward cytokine receptors and inhibitors, and their role in the treatment of atopic and autoinflammatory diseases. RECENT

findingsTranslational research and the identification of the molecular pathophysiology of diseases have led to more targeted treatment approaches. The biologic modulators encompassing monoclonal antibodies as cytokine inhibitors, receptor blocking antibodies, and new fusion receptors are now being applied to diseases beyond their original application. SUMMARY: The expanded use of biological therapies has experienced success in the treatment of numerous disorders, especially in subsets of patients with disease that has been refractory to conventional therapies.

Indexed as

Molecular Targeted TherapyAnaphylaxisAntibodies, MonoclonalAutoantibodiesAutoimmune DiseasesClinical Trials as TopicCytokinesDouble-Blind MethodHumansHypersensitivity, ImmediateImmunoglobulin EImmunosuppressive AgentsInflammationLymphomaRandomized Controlled Trials as TopicReceptors, CytokineAntibodies, MonoclonalAutoantibodiesCytokinesImmunoglobulin EImmunosuppressive AgentsReceptors, CytokineRecombinant Fusion Proteins

Identifiers

PMID21659854
PMCPMC3154953
OpenAlexW1986793620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.