ArticleScience (New York, N.Y.)2011
Cell signaling. New mTOR targets Grb attention.
Article in Science (New York, N.Y.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Real role of growth factor receptor-binding protein 10: Linking lipid metabolism to diabetes cardiovascular complications.World journal of clinical cases · 2022Review
- GRB10 is a novel oncogene associated with cell proliferation and prognosis in glioma.Cancer cell international · 2022Article
- Evodiamine Inhibits Gastric Cancer Cell ProliferationEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Signaling Pathways Involved in the Regulation of mRNA Translation.Molecular and cellular biology · 2018Review
- Lymphangioleiomyomatosis: A Monogenic Model of Malignancy.Annual review of medicine · 2017Review
- The role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistance.Experimental & molecular medicine · 2016Review
- Perturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop.Nucleic acids research · 2015Article
- FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.Molecular oncology · 2013Article
- Knockdown of PRAS40 inhibits insulin action via proteasome-mediated degradation of IRS1 in primary human skeletal muscle cells.Diabetologia · 2013Article
- Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects.Oncogene · 2013Review
- VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.Molecular cancer therapeutics · 2013Article
- Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implications.World journal of virology · 2012Review
- Regulation of mRNA translation by signaling pathways.Cold Spring Harbor perspectives in biology · 2012Review
- Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells.Cancer biology & therapy · 2012Article
- Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.The Journal of biological chemistry · 2012Article
- Akt and mTOR in B Cell Activation and Differentiation.Frontiers in immunology · 2012Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
21659593What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.