ReviewTrends in parasitology2011
Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication.
Review in Trends in parasitology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Eimeria tenella apical membrane 2 overexpression enhances pathogenicity and immunity in chickens.Parasites & vectors · 2025Article
- Key Regulators of Parasite Biology Viewed Through a Post-Translational Modification Repertoire.Proteomics · 2025Review
- The Plasmodium berghei merozoite protein PbGAC is critically involved in erythrocyte binding during invasion.Parasites & vectors · 2025Article
- Proteomic Identification and Functional Analysis ofJournal of tropical medicine · 2025Article
- Adaptations and metabolic evolution of myzozoan protists across diverse lifestyles and environments.Microbiology and molecular biology reviews : MMBR · 2024Review
- Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages.Nature communications · 2024Article
- Natural selection on apical membrane antigen 1 (AMA1) of an emerging zoonotic malaria parasite Plasmodium inui.Scientific reports · 2024Article
- Advances inPathogens (Basel, Switzerland) · 2023Review
- Transmission Cycle of Tick-Borne Infections and Co-Infections, Animal Models and Diseases.Pathogens (Basel, Switzerland) · 2022Review
- Killing the competition: a theoretical framework for liver-stage malaria.Open biology · 2022Article
- Vesicular stomatitis virus-based vaccine targeting plasmodium blood-stage antigens elicits immune response and protects against malaria with protein booster strategy.Frontiers in microbiology · 2022Article
- Identification and Characterization ofMicrobiology spectrum · 2021Article
- Article
- Eimeria tenella Eimeria-specific protein that interacts with apical membrane antigen 1 (EtAMA1) is involved in host cell invasion.Parasites & vectors · 2020Article
- Profiling of myristoylation ineLife · 2020Article
- Further investigation of the characteristics and biological function of Eimeria tenella apical membrane antigen 1.Parasite (Paris, France) · 2020Article
- Overview of PoultryFrontiers in veterinary science · 2020Review
- Glyceraldehyde-3-Phosphate Dehydrogenase ofFrontiers in veterinary science · 2019Article
- Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite.PLoS pathogens · 2018Article
- TheFrontiers in cellular and infection microbiology · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Apicomplexan parasites exhibit an unusual mechanism of host cell penetration. A central player in this process is the protein apical membrane antigen 1 (AMA1). Although essential for invasion, the precise functional roles AMA1 plays have been unclear. Several recent studies have provided important functional insight into its role within the multiprotein complex that comprises the moving junction (MJ). Initially formed at the apical tip of the invading parasite, the MJ represents a ring-like region of contact between the surfaces of the invading parasite and the host cell as the invaginated host plasma membrane is forced inward by the penetrating parasite. This review discusses these and other recent insights into AMA1 with particular emphasis on studies conducted in Plasmodium and Toxoplasma.
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