Evidence map›Paper›PMID 21658829›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2011

Racial and ethnic differences in the association of body mass index and survival in maintenance hemodialysis patients.

Joni Ricks, Miklos Z Molnar, Csaba P Kovesdy, Joel D Kopple, Keith C Norris, Rajnish Mehrotra, Allen R Nissenson, Onyebuchi A Arah, Sander Greenland, Kamyar Kalantar-Zadeh

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

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  16. Longitudinal Weight Change During CKD Progression and Its Association With Subsequent Mortality.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018
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  18. Comparison of Skinfold Thicknesses and Bioimpedance Spectroscopy to Dual-Energy X-Ray Absorptiometry for the Body Fat Measurement in Patients With Chronic Kidney Disease.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Joni RicksHarold Simmons Center for Chronic Disease Research and Epidemiology, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Miklos Z Molnar
Csaba P Kovesdy
Joel D Kopple
Keith C Norris
Rajnish Mehrotra
Allen R Nissenson
Onyebuchi A Arah
Sander Greenland
Kamyar Kalantar-Zadeh
UCLA Medical Center · USUniversity of California, Los Angeles · USAcademic Medical Center · NLHarbor–UCLA Medical Center · USSalem VA Medical Center · USSemmelweis University · HUThe Lundquist Institute · USUCLA Health · US

Funding

Examining Racial and Cardiovascular Paradoxes in Chronic Kidney DiseaseR01DK078106 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KALANTAR-ZADEH, KAMYAR · 2007 to 2011
$1.1M
Understanding Sources of Bias and Outcomes in Peritoneal Dialysis Patient ResearcR21DK077341 · NIDDK · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI KALANTAR-ZADEH, KAMYAR · 2009 to 2010
$409k
NIDDK NIH HHS R01 DK078106NIDDK NIH HHS R21 DK077341
6 · The paper itself

Abstract

backgroundIn maintenance hemodialysis (HD) patients, overweight and obesity are associated with survival advantages. Given the greater survival of maintenance HD patients who are minorities, we hypothesized that increased body mass index (BMI) is associated more strongly with lower mortality in blacks and Hispanics relative to non-Hispanic whites. STUDY

designRetrospective cohort study. SETTING &

participantsWe examined a 6-year (2001-2007) cohort of 109,605 maintenance HD patients including 39,090 blacks, 17,417 Hispanics, and 53,098 non-Hispanic white maintenance HD outpatients from DaVita dialysis clinics. Cox proportional hazards models examined the association between BMI and survival. PREDICTORS: Race and BMI. OUTCOMES: All-cause mortality.

resultsPatients had a mean age of 62 ± 15 (standard deviation) years and included 45% women and 45% patients with diabetes. Across 10 a priori-selected BMI categories (<18-≥40 kg/m(2)), higher BMI was associated with greater survival in all 3 racial/ethnic groups. However, Hispanic and black patients experienced higher survival gains compared with non-Hispanic whites across higher BMI categories. Hispanics and blacks in the ≥40-kg/m(2) category had the largest adjusted decrease in death HR with increasing BMI (0.57 [95% CI, 0.49-0.68] and 0.63 [95% CI, 0.58-0.70], respectively) compared with non-Hispanic whites in the 23- to 25-kg/m(2) group (reference category). In linear models, although the inverse BMI-mortality association was observed for all subgroups, overall black maintenance HD patients showed the largest consistent decrease in death HR with increasing BMI. LIMITATIONS: Race and ethnicity categories were based on self-identified data.

conclusionsWhereas the survival advantage of high BMI is consistent across all racial/ethnic groups, black maintenance HD patients had the strongest and most consistent association of higher BMI with improved survival.

Indexed as

Body Mass IndexRenal DialysisAgedAged, 80 and overBlack or African AmericanBlack PeopleCause of DeathDiagnosis-Related GroupsFemaleHispanic or LatinoHumansKaplan-Meier EstimateKidney Failure, ChronicMaleMiddle AgedObesity

Identifiers

PMID21658829
PMCPMC3183288
OpenAlexW1976968059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.