Evidence map›Paper›PMID 21658615›Full record

ReviewBest practice & research. Clinical haematology2011

Transformation of follicular lymphoma.

Izidore S Lossos, Randy D Gascoyne

Registry-linked trialAbstract readReview
In one paragraph

Review in Best practice & research. Clinical haematology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04587388 (Towards Personalized Medicine for Refractory/Relapsed Follicular Lymphoma Patients), which is not on this map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04587388 unknown statusnot on this mapstarted 2019, after this paper: background citation

Towards Personalized Medicine for Refractory/Relapsed Follicular Lymphoma Patients: the Cantera/Lupiae Registry

Typeobservational_patient_registrySponsorEuropean Hematology Association - Lymphoma GroupRan2019 to 2026Enrolled500ConditionsFollicular Lymphoma, Relapsed/Refractory Follicular Lymphoma
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 167 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Advances in the multi-omics landscape of follicular lymphoma.International journal of biological sciences · 2023
    Review
  15. Review
  16. TdT Positive Lymphoma with MYC, BCL2 and BCL6 Rearrangements: A Review of Diagnosis and Treatment.Mediterranean journal of hematology and infectious diseases · 2022
    Article
  17. Article
  18. Article
  19. Mouse Models in the Study of Mature B-Cell Malignancies.Cold Spring Harbor perspectives in medicine · 2021
    Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Izidore S LossosDepartment of Medicine & Division of Hematology/Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475NW 12th Ave, D8-4, Miami, FL 33136, USA. Ilossos@med.miami.edu
Randy D Gascoyne
Sylvester Comprehensive Cancer Center · USUniversity of British Columbia · CA

Funding

Significance and Function of HGAL in LymphomaR01CA109335 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LOSSOS, IZIDORE S · 2005 to 2013
$2.1M
Prognostic Models in Diffuse Large B-Cell LymphomaR01CA122105 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LOSSOS, IZIDORE S · 2007 to 2010
$1.3M
NCI NIH HHS CA109335NCI NIH HHS CA122105NCI NIH HHS R01 CA109335NCI NIH HHS R01 CA122105
6 · The paper itself

Abstract

Histological transformation of follicular lymphoma (FL) to a more aggressive non-Hodgkin's lymphomas is a pivotal event in the natural history of FL and is associated with poor outcome. While commonly observed in clinical practice and despite multiple studies designed to address its pathogenesis, the biology of this process represents an enigma. In this chapter we present a state of the art review summarizing the definition of histologic transformation, its incidence, pathogenesis, clinical manifestations, treatment and outcome. Furthermore, we specifically emphasize gaps in our knowledge that should be addressed in future studies.

Indexed as

Biomarkers, TumorBiopsyBurkitt LymphomaCell Transformation, NeoplasticChromosome AberrationsDisease-Free SurvivalDisease ProgressionHumansLymphoma, FollicularLymphoma, Large B-Cell, DiffuseMutationPrognosisSalvage TherapyStem Cell TransplantationTransplantation, AutologousBiomarkers, Tumor

Identifiers

PMID21658615
PMCPMC3112479
OpenAlexW1973773204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.