Evidence map›Paper›PMID 21658223›Full record

Trial reportArthritis research & therapy2011

The usefulness of magnetic resonance imaging of the hand and wrist in very early rheumatoid arthritis.

Paraskevi E Kosta, Paraskevi V Voulgari, Anastasia K Zikou, Alexandros A Drosos, Maria I Argyropoulou

Abstract readClinical Trial
In one paragraph

Trial report in Arthritis research & therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Effects of PVA coated nanoparticles on human immune cells.International journal of nanomedicine · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paraskevi E KostaDepartment of Clinical Imaging and Radiology Medical School, University of Ioannina, 45110, Ioannina, Greece.
Paraskevi V Voulgari
Anastasia K Zikou
Alexandros A Drosos
Maria I Argyropoulou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMagnetic resonance imaging (MRI) was used to study the hand and wrist in very early rheumatoid arthritis (RA), and the results were compared with early and established disease.

methodsFifty-seven patients fulfilling the new American College of Rheumatology criteria for RA, 26 with very early RA (VERA), 18 with early RA (ERA), and 13 with established RA (ESTRA), (disease duration < 3 months, < 12 months, and > 12 months, respectively) were enrolled in the study. MRI of the dominant hand and wrist was performed by using fat-suppressed T2-weighted and plain and contrast-enhanced T1-weighted sequences. Evaluation of bone marrow edema, synovitis, and bone erosions was performed with the OMERACT RA MRI scoring system.

resultsEdema, erosions, and synovitis were present in VERA, and the prevalence was 100%, 96.15%, and 92.3%, respectively. Significant differences in edema and erosions were found between VERA and ESTRA (P < 0.05). No significant difference was found in synovitis.

conclusionsEdema, erosions, and synovitis are findings of very early RA. MRI, by detecting these lesions, may play an important role in the management of these patients.

Indexed as

AdolescentAdultAgedAged, 80 and overArthritis, RheumatoidCarpal JointsEarly DiagnosisEdemaFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPrevalenceSynovitisTrapezium Bone

Identifiers

PMID21658223
PMCPMC3218898

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.