Evidence map›Paper›PMID 21657972›Full record

SynthesisActa orthopaedica2011

Obesity in total hip arthroplasty--does it really matter? A meta-analysis.

Daniël Haverkamp, Mark N Klinkenbijl, Mathijs P Somford, G H Rob Albers, Harm M van der Vis

Abstract readMeta-Analysis
In one paragraph

Synthesis in Acta orthopaedica, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Daniël HaverkampDepartment of Orthopaedic Surgery, Tergooi Ziekenhuizen, Hilversum, the Netherlands. Daniel@drhaverkamp.com
Mark N Klinkenbijl
Mathijs P Somford
G H Rob Albers
Harm M van der Vis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeDiscussion persists as to whether obesity negatively influences the outcome of hip arthroplasty. We performed a meta-analysis with the primary research question of whether obesity has a negative effect on short- and long-term outcome of total hip arthroplasty.

methodsWe searched the literature and included studies comparing the outcome of hip arthroplasty in different weight groups. The methodology of the studies included was scored according to the Cochrane guidelines. We extracted and pooled the data. For continuous data, we calculated a weighted mean difference and for dichotomous variables we calculated a weighted odds ratio (OR). Heterogeneity was calculated using I(2) statistics.

results15 studies were eligible for data extraction. In obese patients, dislocation of the hip (OR = 0.54, 95% CI: 0.38-0.75) (10 studies, n = 8,634), aseptic loosening (OR = 0.64, CI: 0.43-0.96) (6 studies, n = 5,137), infection (OR = 0.3, CI: 0.19-0.49) (10 studies, n = 7,500), and venous thromboembolism (OR = 0.56, CI: 0.32-0.98) (7 studies, n = 3,716) occurred more often. Concerning septic loosening and intraoperative fractures, no statistically significant differences were found, possibly due to low power. Subjective outcome measurements did not allow pooling because of high heterogeneity (I(2) = 68%).

interpretationObesity appears to have a negative influence on the outcome of total hip replacement.

Indexed as

Arthroplasty, Replacement, HipHumansIntraoperative ComplicationsObesityOutcome Assessment, Health CarePostoperative ComplicationsProsthesis FailureProsthesis-Related InfectionsTreatment Outcome

Identifiers

PMID21657972
PMCPMC3237030

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.