Evidence map›Paper›PMID 2165768›Full record

ArticleArchives of virology1990

Serotyping of human rotaviruses in Argentina by ELISA with monoclonal antibodies.

J Gómez, M K Estes, D O Matson, R Bellinzoni, A Alvarez, S Grinstein

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

J GómezLaboratorio de Virología Hospital de Niños de Buenos Aires, Argentina.
M K Estes
D O Matson
R Bellinzoni
A Alvarez
S Grinstein
Baylor College of Medicine · USHospital General de Niños Ricardo Gutierrez · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human rotaviruses are the major, recognized cause of infantile diarrhea worldwide. Characterization of naturally occurring human isolates indicates that there are six human rotavirus serotypes, four of which (serotype 1 to 4) are widespread. We utilized monoclonal antibodies specific for the VP of serotypes 1, 2, 3, and 4 as capture antibody in a sandwich enzyme-linked immunosorbent to serotype rotaviruses directly in stool samples. The stool samples were collected from 1983 through 1986, from two epidemiologic studies in the area of Buenos Aires, Argentina. All four serotypes assayed were found Serotype 2 and 3 viruses, which were detected most frequently in 1983 and 1984, were virtually undetected in 1985 and 1986 (chi 2 = 23, P = less than 0.001 for this difference). No significant difference was noted among the three collection sites for serotype prevalence. These results indicate that the changing predominance of rotavirus serotype in a given region can involve multiple serotypes at the same time. Analysis of an outbreak of diarrhea in two neighboring families which occurred during a prospective study of community diarrhea documented inter- and intra-family spread of one serotype of virus.

Indexed as

Antibodies, MonoclonalAntibodies, ViralArgentinaDiarrheaDisease OutbreaksElectrophoresis, Polyacrylamide GelEnzyme-Linked Immunosorbent AssayFecesHumansRNA, Double-StrandedRNA, ViralRotavirusSerotypingAntibodies, MonoclonalAntibodies, ViralRNA, Double-StrandedRNA, Viral

Identifiers

PMID2165768
OpenAlexW2083751638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.