Evidence map›Paper›PMID 21656324›Full record

SynthesisSurgical endoscopy2011

Endoscopic necrosectomy of pancreatic necrosis: a systematic review.

Alireza Haghshenasskashani, Jerome M Laurence, Vu Kwan, Emma Johnston, Michael J Hollands, Arthur J Richardson, Henry C C Pleass, Vincent W T Lam

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02673541 (Randomized, Multi-Center, Comparative and Cost Effectiveness Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02673541 naterminatednot on this mapstarted 2016, after this paper: background citation

Randomized, Multi-Center, Comparative and Cost Effectiveness Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent (Axios™) Versus Multiple Double Pigtail Stents in the Management of Walled Off Pancreatic Necrosis

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2016 to 2017Enrolled5ConditionsPancreatic NecrosisArmsAXIOS™ stent, Double Pigtail Stents
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Minimally invasive surgery compared to endoscopic intervention for treating infected pancreatic necrosis. A meta-analysis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
    Article
  6. Article
  7. Endoscopic therapies for walled-off necrosis.iGIE : innovation, investigation and insights · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Pancreatic necrosis: Complications and changing trend of treatment.World journal of gastrointestinal surgery · 2019
    Review
  13. Article
  14. Endoscopic management of pancreatic ascites due to duct disruption following acute necrotizing pancreatitis.JGH open : an open access journal of gastroenterology and hepatology · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Endoscopic ultrasound-guided transmural drainage of walled-off pancreatic necrosis in patients with portal hypertension and intra-abdominal collaterals.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alireza HaghshenasskashaniDepartment of Surgery, Westmead Hospital, PO Box 533, Wentworthville, Sydney, NSW 2145, Australia.
Jerome M Laurence
Vu Kwan
Emma Johnston
Michael J Hollands
Arthur J Richardson
Henry C C Pleass
Vincent W T Lam
Westmead Hospital · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo review the current status of the novel technique of endoscopic necrosectomy in the management of pancreatic necrosis after acute pancreatitis.

methodsStudies were identified by searching Medline, PubMed and Embase databases for articles from January 1990 to December 2009 using the keywords "acute pancreatitis", "pancreatic necrosis" and "endoscopy". Additional papers were identified by a manual search of the references from the key articles. Case series of fewer than five patients and case reports were excluded.

resultsIndications, techniques and outcomes of endoscopic necrosectomy were analysed. There were no randomised controlled trials identified. Ten case series were included in this analysis. There were a total of more than 1,100 endoscopic necrosectomy procedures in 260 patients with pancreatic necrosis. One hundred fifty-five were proven to be infected necrosis on culture. The overall mortality rate was 5%. The mean procedure-related morbidity rate was 27%. The rate of complete resolution of pancreatic necrosis with the endoscopic method alone was 76%.

conclusionsEndoscopic necrosectomy is a safe and effective treatment option in selected patients with pancreatic necrosis after acute pancreatitis. Future studies will be required to further define the selection criteria and the techniques for the endoscopic procedure.

Indexed as

Acute DiseaseAdolescentAdultAgedAged, 80 and overEndoscopy, Digestive SystemFemaleHumansMaleMiddle AgedNecrosisPancreasPancreatitisTreatment OutcomeYoung Adult

Identifiers

PMID21656324
OpenAlexW2038842787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.