Evidence map›Paper›PMID 21656311›Full record

ArticleJournal of genetic counseling2011

Differences between African American and White research volunteers in their attitudes, beliefs and knowledge regarding genetic testing for Alzheimer's disease.

Ibidapo Akinleye, J Scott Roberts, Charmaine D M Royal, Erin Linnenbringer, Thomas O Obisesan, Grace-Ann Fasaye, Robert C Green

Abstract readComparative Study
In one paragraph

Article in Journal of genetic counseling, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Psychosocial implications of learning amyloid PET results in an observational cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Observational
  5. Article
  6. Reasons for undergoing amyloid imaging among cognitively unimpaired older adults.Annals of clinical and translational neurology · 2021
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Race, Genomics and Chronic Disease: What Patients with African Ancestry Have to Say.Journal of health care for the poor and underserved · 2017
    Article
  13. Article
  14. Effects of racial and ethnic group and health literacy on responses to genomic risk information in a medically underserved population.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2015
    Article
  15. Perceptions of genetic testing and genomic medicine among drug users.The International journal on drug policy · 2015
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ibidapo AkinleyeDepartment of Epidemiology, University of Albany School of Public Health, Albany, NY, USA.
J Scott Roberts
Charmaine D M Royal
Erin Linnenbringer
Thomas O Obisesan
Grace-Ann Fasaye
Robert C Green

Funding

Neuropathology CoreP30AG013846 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOWALL, NEIL W. · 1996 to 2020
$29.1M
YOGA INDUCED CHANGES IN BRAIN GABA LEVELSM01RR000533 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HOLICK, MICHAEL F. · 1985 to 2008
$19.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025771 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CENTER, DAVID M. · 2008 to 2011
$17.6M
GENETIC EPIDEMIOLOGICAL STUDIES OF ALZHEIMERS DISEASER01AG009029 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FARRER, LINDSAY A. · 1991 to 2007
$14.7M
Risk Evaluation and Education for Alzheimer's Disease (REVEAL IV)R01HG002213 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C. · 1999 to 2012
$7.6M
Impact of Direct to Consumer Genetic TestingR01HG005092 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C., ROBERTS, SCOTT · 2010 to 2012
$1.1M
Characterizing Communicating Genetic Risk Alzheimer'sK24AG027841 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C. · 2006 to 2010
$914k
NCRR NIH HHS M01 RR000533NCRR NIH HHS UL1 RR025771NHGRI NIH HHS R01 HG002213NHGRI NIH HHS R01 HG005092NHGRI NIH HHS R01-HG005092NHGRI NIH HHS R01-HG02213NIA NIH HHS K24 AG027841NIA NIH HHS K24-AG027841NIA NIH HHS P30 AG013846NIA NIH HHS P30-AG13846NIA NIH HHS R01 AG009029NIA NIH HHS R01-AG09029
6 · The paper itself

Abstract

Genetic susceptibility testing for common diseases is expanding, but little is known about race group differences in test perceptions. The purpose of this study was to examine differences between African Americans and Whites in knowledge, attitudes, and motivations regarding genetic susceptibility testing for Alzheimer's disease (AD). Before enrolling in an AD genetic testing research trial, 313 first-degree relatives of AD patients (20% African American; 71% female; mean age = 58 years) were surveyed regarding: (1) knowledge about genetics and AD risk; (2) concerns about developing AD; and (3) reasons for seeking testing. In comparison to Whites, African Americans were less knowledgeable about genetics and AD risk (p < .01) and less concerned about developing AD (p < .05), with lower levels of perceived disease risk (p = .04). The results suggest that African Americans and Whites differ notably in their knowledge, beliefs, and attitudes regarding genetic testing for AD. Additional research with more representative samples is needed to better understand these differences.

Indexed as

Black PeopleHealth Knowledge, Attitudes, PracticeWhite PeopleAdultAlzheimer DiseaseBlack or African AmericanFemaleGenetic TestingHumansMaleMiddle Aged

Identifiers

PMID21656311
PMCPMC3223287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.