ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2011
Weight loss and low-intensity exercise for the treatment of metabolic syndrome in obese postmenopausal women.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- Enjoyment of high-intensity interval training in an overweight/obese cohort: a short report.Clinical physiology and functional imaging · 2017Trial
- Circulating cytokines as determinants of weight loss-induced improvements in insulin sensitivity.Endocrine · 2017 · on this mapTrial
- Effects of a 12-month physical activity intervention on prevalence of metabolic syndrome in elderly men and women.The journals of gerontology. Series A, Biological sciences and medical sciences · 2012Trial
- Exercise training with weight loss and either a high- or low-glycemic index diet reduces metabolic syndrome severity in older adults.Annals of nutrition & metabolism · 2012 · on this mapTrial
- Does Lifestyle Exercise After a Cardiac Event Improve Metabolic Syndrome Profile in Older Adults?The Journal of cardiovascular nursingTrial
- Poly is more effective than monounsaturated fat for dietary management in the metabolic syndrome: The muffin study.Journal of clinical lipidologyTrial
- Serum IL-6 and sIL-6R in type 2 diabetes contribute to impaired capillary-like network formation.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Article
- Short-term exercise training improves flow-mediated dilation and circulating angiogenic cell number in older sedentary adults.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016Article
- Article
- Exercise Training and Insulin Resistance: A Current Review.Journal of obesity & weight loss therapy · 2015Article
- Screening premorbid metabolic syndrome in community pharmacies: a cross-sectional descriptive study.BMC public health · 2014Article
- Does hormone therapy affect blood pressure changes in the Diabetes Prevention Program?Menopause (New York, N.Y.) · 2014Article
- Article
- Low clonogenic potential of circulating angiogenic cells is associated with lower density of capillaries in skeletal muscle in patients with impaired glucose tolerance.Diabetes/metabolism research and reviews · 2013Article
- Walking promotes metabolic and baroreflex sensitivity improvement in fructose-fed male rats.European journal of applied physiology · 2013Article
- The effect of stability and change in health behaviors on trajectories of body mass index in older Americans: a 14-year longitudinal study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2012Article
- Impact of a physician-supervised exercise-nutrition program with testosterone substitution in partial androgen-deficient middle-aged obese men.Journal of geriatric cardiology : JGC · 2011Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe prevalence of the metabolic syndrome (MetSyn) approaches 50% in postmenopausal women. This study examines the efficacy of lifestyle modification for the treatment of MetSyn and its associated risk for cardiovascular disease and diabetes in this population.
methodsThis prospective controlled study examines the effects of a 6-month weight loss and low-intensity exercise program (WL+LEX) on body composition (dual-energy X-ray absorptiometry and abdominal computed tomography scans), fasting glucose and lipid levels, cytokines, and blood pressure in postmenopausal women with and without MetSyn.
resultsWL+LEX reduced body weight (MetSyn: -5% vs non-MetSyn: -7%) and fat mass (-11% vs -15%) and increased VO(2max) (+2% vs +3%) in both MetSyn (N = 35) and non-MetSyn (N = 41) groups. Constituents of MetSyn decreased comparably in both groups. Fifteen (45%) MetSyn participants responded (R) by converting to non-MetSyn, 18 remained MetSyn (NR), and 2 had missing data. Reduction in fat mass (-15% vs -8%, p = .02) was greater in R than NR, but there were no between-group differences in changes in VO(2max), cytokines, or other variables. The decrease in the number of MetSyn criteria was greater in R than in NR (-27 vs -13, p < .0001) due to decreases in blood pressure (p < .01), glucose (p = .02), and with a trend for triglyceride (p = .07). Reductions in fat mass best predicted resolution of MetSyn (p = .04).
conclusionsWomen who lose more fat are more likely to lower blood pressure, glucose, and triglyceride levels to resolve MetSyn. Thus, a WL+LEX program effectively treats postmenopausal women with MetSyn.
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