Evidence map›Paper›PMID 21653547›Full record

ArticleNucleic acids research2011

PILGRM: an interactive data-driven discovery platform for expert biologists.

Casey S Greene, Olga G Troyanskaya

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Using genome-wide expression compendia to study microorganisms.Computational and structural biotechnology journal · 2022
    Review
  3. NewG3 (Bethesda, Md.) · 2019
    Article
  4. Machine Learning Analysis IdentifiesG3 (Bethesda, Md.) · 2017
    Article
  5. Big Data Bioinformatics.Methods (San Diego, Calif.) · 2016
    Article
  6. Article
  7. Review
  8. COMPUTATIONAL APPROACHES TO STUDY MICROBES AND MICROBIOMES.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2016
    Article
  9. Implications of Big Data for cell biology.Molecular biology of the cell · 2015
    Article
  10. Big data bioinformatics.Journal of cellular physiology · 2014
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Accurate evaluation and analysis of functional genomics data and methods.Annals of the New York Academy of Sciences · 2012
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Casey S GreeneDepartment of Computer Science, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA. csgreene@princeton.edu
Olga G Troyanskaya
Princeton University · US

Funding

Spatial Patterning During DevelopmentP50GM071508 · NIGMS · PRINCETON UNIVERSITY · PI POWELL, SUSAN M · 2004 to 2013
$30.6M
lntegration and Visualization of Diverse Biological DataR01GM071966 · NIGMS · PRINCETON UNIVERSITY · PI TROYANSKAYA, OLGA G · 2005 to 2022
$6.4M
Context-Sensitive Search of Human Expression CompendiaR01HG005998 · NHGRI · PRINCETON UNIVERSITY · PI TROYANSKAYA, OLGA G · 2011 to 2013
$1.1M
NCI NIH HHS T32 CA005928NHGRI NIH HHS R01 HG005998NIGMS NIH HHS P50 GM071508NIGMS NIH HHS R01 GM071966
6 · The paper itself

Abstract

PILGRM (the platform for interactive learning by genomics results mining) puts advanced supervised analysis techniques applied to enormous gene expression compendia into the hands of bench biologists. This flexible system empowers its users to answer diverse biological questions that are often outside of the scope of common databases in a data-driven manner. This capability allows domain experts to quickly and easily generate hypotheses about biological processes, tissues or diseases of interest. Specifically PILGRM helps biologists generate these hypotheses by analyzing the expression levels of known relevant genes in large compendia of microarray data. Because PILGRM is data-driven, it complements a user's knowledge and literature analysis with mining of diverse functional genomic data, thereby generating novel predictions that can drive experimental follow-up. This server is free, does not require registration and is available for use at http://pilgrm.princeton.edu.

Indexed as

Gene Expression ProfilingSoftwareAnimalsDatabases, GeneticData MiningDNA RepairHumansInternetMiceRatsUser-Computer Interface

Identifiers

PMID21653547
PMCPMC3125802
OpenAlexW2117262895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.