Evidence map›Paper›PMID 21653528›Full record

ReviewProceedings of the American Thoracic Society2011

HIV-associated lung infections and complications in the era of combination antiretroviral therapy.

Kristina Crothers, Bruce W Thompson, Kathryn Burkhardt, Alison Morris, Sonia C Flores, Philip T Diaz, Richard E Chaisson, Gregory D Kirk, William N Rom, Laurence Huang and 1 more

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Proceedings of the American Thoracic Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00933595 nacompletednot on this map

Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV)

TypeinterventionalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran2007 to 2013ConditionsPulmonary Complications, HIV InfectionsArmsSmoking Cessation
NCT02975258 completednot on this mapstarted 2015, after this paper: background citation

Adiposity and Airway Inflammation in HIV-Associated Airway Disease

TypeobservationalSponsorUniversity of PittsburghRan2015 to 2017Enrolled102ConditionsAsthma, HIV, AdiposityArmsBlood draw, Questionnaires, Spirometry, Methacholine challenge test, Quantitative CT scans
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

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  5. Safety of varenicline among smokers enrolled in the lung HIV study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Kristina CrothersDivision of Pulmonary and Critical Care, Department of Internal Medicine, University of Washington, Seattle, Washington, USA.
Bruce W Thompson
Kathryn Burkhardt
Alison Morris
Sonia C Flores
Philip T Diaz
Richard E Chaisson
Gregory D Kirk
William N Rom
Laurence Huang
Lung HIV Study
Clinical Trials and Surveys Corporation · USJohns Hopkins University · USNew York University · USSan Francisco General Hospital · USThe Ohio State University · USTrinity Baptist College · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Pittsburgh · USUniversity of Washington · US

Funding

The Study of HIV Infection in the Etiology of Lung Disease (SHIELD)R01HL090483 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KIRK, GREGORY D · 2007 to 2011
$4.4M
Longtitudinal Studies of HIV-Associated Bacterial PneumoniaR01HL090316 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ROM, WILLIAM N · 2007 to 2013
$4.2M
Longitudinal Studies of HIV-Associated Lung Infections and Complications - DCCR01HL090331 · NHLBI · CLINICAL TRIALS AND SURVEYS CORPORATION · PI THOMPSON, BRUCE WILLIAM · 2007 to 2011
$4.1M
Longitudinal Studies of HIV-Associated Lung Infections and ComplicationsR01HL090342 · NHLBI · YALE UNIVERSITY · PI CROTHERS, KRISTINA ANNE · 2007 to 2011
$4.0M
Prevalence & Pathogenesis of Pulmonary Disease in a Large Multicenter HIV CohortR01HL090339 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MORRIS, ALISON · 2007 to 2011
$4.0M
International HIV-associated Opportunistic Pneumonias (IHOP) StudyR01HL090335 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, LAURENCE · 2007 to 2011
$4.0M
Longitudinal studies of HIV-1 Nef in Pulmonary HypertensionR01HL090480 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI FLORES, SONIA CASTRO · 2007 to 2011
$3.9M
Smoking cessation and the natural history of HIV-associated emphysemaR01HL090313 · NHLBI · OHIO STATE UNIVERSITY · PI DIAZ, PHILIP T · 2007 to 2011
$3.9M
Longitudinal Study of HIV-Associated Lung Infections in SowetoR01HL090312 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHAISSON, RICHARD E. · 2007 to 2012
$3.3M
Patient-Oriented Research and Mentoring in PneumocystisK24HL087713 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, LAURENCE · 2006 to 2018
$1.8M
MOLECULAR BIOLOGY OF INTRINSIC ACTIVATION OF FACTOR XF32HL007008 · NHLBI · SCRIPPS CLINIC AND RESEARCH FOUNDATION · PI BURRI, BETTY J · 1985 to 1985
–
NHLBI NIH HHS HL-07-008NHLBI NIH HHS K24 HL087713NHLBI NIH HHS R01 HL090312NHLBI NIH HHS R01-HL090312NHLBI NIH HHS R01-HL090313NHLBI NIH HHS R01-HL090316NHLBI NIH HHS R01-HL090331NHLBI NIH HHS R01 HL090335NHLBI NIH HHS R01-HL090335NHLBI NIH HHS R01-HL090339NHLBI NIH HHS R01-HL090342NHLBI NIH HHS R01-HL090480NHLBI NIH HHS R01-HL090483
6 · The paper itself

Abstract

The spectrum of lung diseases associated with HIV is broad, and many infectious and noninfectious complications of HIV infection have been recognized. The nature and prevalence of lung complications have not been fully characterized since the Pulmonary Complications of HIV Infection Study more than 15 years ago, before antiretroviral therapy (ART) increased life expectancy. Our understanding of the global epidemiology of these diseases in the current ART era is limited, and the mechanisms for the increases in the noninfectious conditions, in particular, are not well understood. The Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV) Study (ClinicalTrials.gov number NCT00933595) is a collaborative multi-R01 consortium of research projects established by the National Heart, Lung, and Blood Institute to examine a diverse range of infectious and noninfectious pulmonary diseases in HIV-infected persons. This article reviews our current state of knowledge of the impact of HIV on lung health and the development of pulmonary diseases, and highlights ongoing research within the Lung HIV Study.

Indexed as

AIDS-Related Opportunistic InfectionsAnti-Retroviral AgentsCD4 Lymphocyte CountClinical Trials as TopicHIV InfectionsHumansLungLung DiseasesMulticenter Studies as TopicRisk FactorsT-LymphocytesAnti-Retroviral Agents

Identifiers

PMID21653528
PMCPMC3132785
OpenAlexW2062422490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.