Evidence map›Paper›PMID 21652590›Full record

ArticleJournal of child neurology2011

A sensitive diffusion tensor imaging quantification method to detect language laterality in children: correlation with the Wada test.

Vijay Narayan Tiwari, Jeong-Won Jeong, Eishi Asano, Robert Rothermel, Csaba Juhasz, Harry T Chugani

Open access · greenAbstract read
In one paragraph

Article in Journal of child neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Associations between Cortical Asymmetry and Domain Specific Cognitive Functions in Healthy Children.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. Multimodality language mapping in patients with left-hemispheric language dominance on Wada test.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vijay Narayan TiwariDepartment of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan, USA.
Jeong-Won Jeong
Eishi Asano
Robert Rothermel
Csaba Juhasz
Harry T Chugani
Children's Hospital of Michigan · USWayne State University · US

Funding

Functional brain mapping in pediatric neurosurgeryR01NS064033 · NINDS · WAYNE STATE UNIVERSITY · PI EISHI ASANO · 2009 to 2026
$5.7M
LOCALIZATION OF EPILEPTIC FOCI WITH PET IN CHILDRENR01NS034488 · NINDS · WAYNE STATE UNIVERSITY · PI CHUGANI, HARRY · 1997 to 2009
$3.6M
NINDS NIH HHS R01 NS034488NINDS NIH HHS R01 NS064033
6 · The paper itself

Abstract

Using diffusion tensor imaging tractography and color-coded anisotropy map quantification, we investigated asymmetry of the arcuate fasciculus to determine language laterality in children and compared it with the Wada test. Arcuate fasciculus volume and fractional anisotropy were measured after tractography. We also quantified the fiber orientation distribution in the arcuate fasciculus region, ie, the fraction of arcuate fasciculus fibers oriented in the anteroposterior and mediolateral directions. A Laterality Index was calculated for each of the measured parameters. Volumetric analysis of the arcuate fasciculus showed asymmetry favoring the language dominant hemisphere (P = .02), while fractional anisotropy showed no significant asymmetry (P = .07). The mean anteroposterior and mediolateral components on the language dominant side were significantly higher than on the nondominant side (P = .003 and .002, respectively). The Laterality Index values were concordant with the Wada test results except for 1 case. Fractional anisotropy also falsely lateralized language in 1 case.

Indexed as

Brain MappingDiffusion Tensor ImagingLanguageNeurologic ExaminationAdolescentAnisotropyChildChild, PreschoolEpilepsyFemaleFunctional LateralityHumansMaleNerve Fibers, Myelinated

Identifiers

PMID21652590
PMCPMC3673532
OpenAlexW2011757669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.