ArticleJournal of experimental botany2011
A mobile signal transported over a long distance induces systemic transcriptional gene silencing in a grafted partner.
Article in Journal of experimental botany, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 79 citations in OpenAlex.
- Fungal MicroRNA-Like RNAs Facilitate Convergent Attack on a Host Immune Signalling Network.Plant, cell & environment · 2026Article
- Bridging the Gap: Genetic Insights into Graft Compatibility for Enhanced Kiwifruit Production.International journal of molecular sciences · 2025Review
- Single-Base Methylome Analysis of Sweet Cherry (International journal of molecular sciences · 2024Article
- Transcriptomics Identifies Differentially Expressed Genes Inducing Tuber Formation in Early- and Late-Maturing Potatoes.Plants (Basel, Switzerland) · 2024Article
- Long distance signalling and epigenetic changes in crop grafting.Frontiers in plant science · 2023Review
- Grafting vigour is associated with DNA de-methylation in eggplant.Horticulture research · 2021Article
- Two pathogenesis-related proteins interact with leucine-rich repeat proteins to promote Alternaria leaf spot resistance in apple.Horticulture research · 2021Article
- Secondary siRNAs in Plants: Biosynthesis, Various Functions, and Applications in Virology.Frontiers in plant science · 2021Review
- Systemic GFP silencing is associated with high transgene expression in Nicotiana benthamiana.PloS one · 2021Article
- RNA-directed DNA Methylation.PLoS genetics · 2020Article
- Vegetable Grafting From a Molecular Point of View: The Involvement of Epigenetics in Rootstock-Scion Interactions.Frontiers in plant science · 2020Review
- Mechanisms Underlying Graft Union Formation and Rootstock Scion Interaction in Horticultural Plants.Frontiers in plant science · 2020Review
- Plant Noncoding RNAs: Hidden Players in Development and Stress Responses.Annual review of cell and developmental biology · 2019Review
- Systemic signalling through translationally controlled tumour protein controls lateral root formation in Arabidopsis.Journal of experimental botany · 2019Article
- A Single-Nucleotide Polymorphism in the Promoter of a Hairpin RNA Contributes toThe Plant cell · 2018Article
- Sorbitol Modulates Resistance toThe Plant cell · 2018Article
- Md-miR156ab and Md-miR395 Target WRKY Transcription Factors to Influence Apple Resistance to Leaf Spot Disease.Frontiers in plant science · 2017Article
- Article
- Biotechnology and apple breeding in Japan.Breeding science · 2016Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcriptional gene silencing (TGS) can be induced by promoter-targeted small interfering RNA (siRNA). Long-distance transmission of TGS by viral infection in plants has been reported. However, systemic TGS has not been observed in the case of using an inverted repeat transgene as the silencing trigger. Here it is reported that a mobile signal, presumably the siRNA, produced from a hairpin structure transgene controlled by a companion cell-specific promoter can also induce transmissible TGS in both a modified agroinfiltration and a grafting system. Although the transmissible TGS occurred only in cells located in the vicinity of a leaf vein in the scion, very strong silencing was observed in the root system, especially the lateral roots, including the root apical meristem. The transmissible TGS was maintained through tissue culture and subsequently inherited by the progeny. The results suggest the potential application of mobile promoter-targeting siRNA in horticulture for improvement of plant cultivars by grafting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.