Evidence map›Paper›PMID 21651805›Full record

Trial reportTrials2011

The Home-Based Older People's Exercise (HOPE) trial: study protocol for a randomised controlled trial.

Andrew Clegg, Sally Barber, John Young, Anne Forster, Steve Iliffe

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03008135 (Reliability and Validity of the Elderly Mobility Scale for Frailty People Living at Home, French Version), which is not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03008135 completednot on this mapstarted 2017, after this paper: background citation

Reliability and Validity of the Elderly Mobility Scale for Frailty People Living at Home, French Version

TypeobservationalSponsorPole Santé Plouasne Saint Pern BecherelRan2017 to 2017Enrolled25ConditionsLocomotor Activity, Functionally-Impaired Elderly, Frail ElderlyArmsElderly Mobility Scale, Frailty scale
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Quality of life is substantially worse for community-dwelling older people living with frailty: systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Pooled it
  2. Exercise for depression.The Cochrane database of systematic reviews · 2013
    Pooled it
  3. Interventions for preventing falls in older people living in the community.The Cochrane database of systematic reviews · 2012
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Article
  10. Observational
  11. Osteoporosis and cancer.Current osteoporosis reports · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrew CleggAcademic Unit of Elderly Care & Rehabilitation, University of Leeds, Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Duckworth Lane, Bradford BD9 6RJ, UK. andrewpaulclegg@yahoo.co.uk
Sally Barber
John Young
Anne Forster
Steve Iliffe
University of Leeds · GBBradford Teaching Hospitals NHS Foundation Trust · GBUniversity College London · GB

Funding

The Dunhill Medical Trust RCP/DMT 2ND ROUND (2)
6 · The paper itself

Abstract

backgroundFrailty is common in older age, and is associated with important adverse health outcomes including increased risk of disability and admission to hospital or long-term care. Exercise interventions for frail older people have the potential to reduce the risk of these adverse outcomes by increasing muscle strength and improving mobility. METHODS/

designThe Home-Based Older People's Exercise (HOPE) trial is a two arm, assessor blind pilot randomised controlled trial (RCT) to assess the effectiveness of a 12 week exercise intervention (the HOPE programme) designed to improve the mobility and functional abilities of frail older people living at home, compared with usual care. The primary outcome is the timed-up-and-go test (TUGT), measured at baseline and 14 weeks post-randomisation. Secondary outcomes include the Barthel Index of activities of daily living (ADL), EuroQol Group 5-Dimension Self-Report Questionnaire (EQ-5D) quality of life measure and the geriatric depression scale (GDS), measured at baseline and 14 weeks post-randomisation. We will record baseline frailty using the Edmonton Frail Scale (EFS), record falls and document muscle/joint pain. We will test the feasibility of collection of data to identify therapy resources required for delivery of the intervention. DISCUSSION: The HOPE trial will explore and evaluate a home-based exercise intervention for frail older people. Although previous RCTs have used operationalised, non-validated methods of measuring frailty, the HOPE trial is, to our knowledge, the first RCT of an exercise intervention for frail older people that includes a validated method of frailty assessment at baseline.

trial registrationISRCTN: ISRCTN57066881.

Indexed as

Exercise TherapyHealth Services for the AgedHome Care ServicesIndependent LivingResearch DesignAccidental FallsAgedAged, 80 and overAgingDepressionEnglandFeasibility StudiesFrail ElderlyHumansMuscle, SkeletalMuscle Strength

Identifiers

PMID21651805
PMCPMC3121609
OpenAlexW2122934004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.