ReviewExpert review of neurotherapeutics2011
Brain functional domains inform therapeutic interventions in attention-deficit/hyperactivity disorder and pediatric bipolar disorder.
Review in Expert review of neurotherapeutics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
- Mediators in the randomized trial of Child- and Family-Focused Cognitive-Behavioral Therapy for pediatric bipolar disorder.Behaviour research and therapy · 2016Trial
- Child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: a randomized clinical trial.Journal of the American Academy of Child and Adolescent Psychiatry · 2014Trial
- Pharmacotherapy impacts functional connectivity among affective circuits during response inhibition in pediatric mania.Behavioural brain research · 2012Trial
- The shared and disorder-specific resting-state functional connectivity networks associated with emotion regulation between attention deficit/hyperactivity disorder and bipolar disorder.Brain imaging and behavior · 2026Article
- Segregation, integration and balance in resting-state brain functional networks associated with bipolar disorder symptoms.Human brain mapping · 2023Article
- A Preliminary Study on the Functional Benefits of Computerized Working Memory Training in Children With Pediatric Bipolar Disorder and Attention Deficit Hyperactivity Disorder.Frontiers in psychology · 2019Article
- Longitudinal Diffusion Tensor Imaging Study of Adolescents and Young Adults With Bipolar Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2018Article
- Cognitive Neuroscience of Attention Deficit Hyperactivity Disorder (ADHD) and Its Clinical Translation.Frontiers in human neuroscience · 2018Review
- Differences in Real World Executive Function between Children with Pediatric Bipolar Disorder and Children with ADHD.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2016Article
- White matter structure in youth with behavioral and emotional dysregulation disorders: a probabilistic tractographic study.JAMA psychiatry · 2015Article
- Distinguishing bipolar disorder from other psychiatric disorders in children.Current psychiatry reports · 2014Review
- From neural signatures of emotional modulation to social cognition: individual differences in healthy volunteers and psychiatric participants.Social cognitive and affective neuroscience · 2014Article
- A systems neuroscience approach to the pathophysiology of pediatric mood and anxiety disorders.Current topics in behavioral neurosciences · 2014Review
- Time course of recovery showing initial prefrontal cortex changes at 16 weeks, extending to subcortical changes by 3 years in pediatric bipolar disorder.Journal of affective disorders · 2013Article
- Negative emotion impairs working memory in pediatric patients with bipolar disorder type I.Psychological medicine · 2012Article
- Reduced functional connectivity of prefrontal regions and amygdala within affect and working memory networks in pediatric bipolar disorder.Brain connectivity · 2012Article
- Amygdala functional connectivity predicts pharmacotherapy outcome in pediatric bipolar disorder.Brain connectivity · 2011Article
- Preterm Birth Causes Decreased Postnatal Neurogenesis: A Novel Mechanism Underlying Adverse Neurodevelopmental Outcomes.Pediatrics international : official journal of the Japan Pediatric SocietyReview
- Applying a Cognitive Neuroscience Perspective to Disruptive Behavior Disorders: Implications for Schools.Developmental neuropsychologyArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
A deeper understanding of how the relationships between impulsivity, reward systems and executive function deficits may be similar or different in attention-deficit/hyperactivity disorder (ADHD) and pediatric bipolar disorder (PBD) is fundamental for better defining phenotypy in these two developmental illnesses, and moving towards improved treatment and intervention. We focus our article on recent neurocognitive and neuroimaging data examining the behavioral and neural aspects of poor behavior regulation, response inhibition and reward systems in ADHD and PBD. In light of recent research evidence, we propose that the common behavioral manifestations of impulsivity in ADHD and PBD may indeed originate from different neural mechanisms mediated by altered reward systems. In order to define and differentiate these mechanisms, unlike previous approaches, our theoretical model examines the interface of the dorsal frontostriatal circuit, involved in behavior regulation, and the ventral frontostriatal circuit, which is involved in reward-related and affect processes. Preliminary evidence suggests that the neural systems involved in impulsivity, reward systems and executive function engage differently in the two illnesses. In PBD, 'emotional impulsivity' is predominantly 'bottom-up' and emotionally/motivationally driven, and stems from ventral frontostriatal circuitry dysfunction. By contrast, in ADHD 'cognitive impulsivity' is predominantly 'top-down' and more 'cognitively driven', and stems from dorsal frontostriatal dysfunction. We discuss this evidence in view of clinically relevant questions and implications for illness-based intervention. We conclude that the reward-related mechanisms underlying the interactions between executive function, behavior regulation and impulsivity in PBD and ADHD may be differentially compromised, and in accordance differently shape the clinical symptoms of impulsivity and goal-directed behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.